Evidence map›Paper›PMID 41670926›Full record

ArticleJournal of clinical immunology2026

WAS Protein Deficiency Disrupts Memory B Cell Formation During Acute LCMV Infection.

Liang Zhang, Yongjie Liu, Dujuan Zhou

Abstract read
In one paragraph

Article in Journal of clinical immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liang Zhang *The Affiliated Children's Hospital of Xiangya School of Medicine, Central South University (Hunan Children's Hospital), Changsha, 410007, Hunan, China. 1374786384@qq.com.
Yongjie Liu *The Affiliated Children's Hospital of Xiangya School of Medicine, Central South University (Hunan Children's Hospital), Changsha, 410007, Hunan, China.
Dujuan ZhouDepartment of Pediatric Nephrology, Rheumatology and Immunology, the First People's Hospital of Chenzhou, Chenzhou, 423000, Hunan, China.

Funding

National Natural Science Foundation of China 82101962
6 · The paper itself

Abstract

Wiskott-Aldrich syndrome (WAS) is a rare x-linked monogenic immunodeficiency disease, caused by the mutation of WAS gene encoding WAS protein (WASp). Previous findings in WAS patients show B cell perturbations in the periphery, characterized by diminished B-cell numbers and phenotype abnormalities, including reduced frequency of classical CD27

Indexed as

Immunologic MemoryLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMemory B CellsWiskott-Aldrich SyndromeWiskott-Aldrich Syndrome ProteinAcute DiseaseAnimalsCell DifferentiationDisease Models, AnimalHumansMiceMice, KnockoutWas protein, mouseWiskott-Aldrich Syndrome Proteincell differentiationImmunodeficiencymemory B cellsscRNA-seqWiskott-Aldrich syndrome

Identifiers

PMID41670926
PMCPMC12950028

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.