Evidence map›Paper›PMID 41670682›Full record

ArticleSocial psychiatry and psychiatric epidemiology2026

Early childhood and early adolescent predictors of internalising symptoms in adolescents: findings from a longitudinal study in a high-risk South African environment.

Stefani Du Toit, Katharina Haag, Mark Tomlinson, Lorraine Sherr, Marguerite Marlow, Jackie Stewart, Sarah Skeen

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Article in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Stefani Du ToitInstitute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa. dutoits@sun.ac.za.ORCID http://orcid.org/0000-0001-7947-3043
Katharina HaagInstitute for Global Health, University College London, London, UK.
Mark TomlinsonInstitute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa.
Lorraine SherrInstitute for Global Health, University College London, London, UK.
Marguerite MarlowInstitute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa.
Jackie StewartThe Division of Global Surgery, Department of Surgery, University of Cape Town, Cape Town, South Africa.
Sarah SkeenInstitute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigates predictors of internalising symptoms among adolescents aged 16 to 19 years in a high-risk context in South Africa. Specifically, it explores early childhood (antenatal to 18 months postpartum), and early adolescent (13 to 14 years) predictors of internalising symptoms measured during later adolescence (16-19 years), aiming to identify key factors influencing mental health outcomes in this vulnerable population.

methodsUtilising a unique 18-year longitudinal dataset, we included a total of 314 adolescent participants from South Africa in the analysis and employed an adaptive elastic net regularised regression to analyse the effects of 18 predictors from early childhood and early adolescence on internalising symptoms at ages 16 to 19 years. The broadband scale for "internalising" from the Youth Self Report (ages 11-18) was used as the outcome measure. Data collected at five time points across three phases of the longitudinal study were included in the analysis.

resultsKey predictors of internalising symptoms were female sex (β=-4.30; 95% CI [-4.42;4.19]). Early childhood predictors with significant associations were maternal depression (β = 1.70; 95% CI [1.56;1.84]) and caregiver employment (β=-0.37; 95% CI [-0.46;-0.29]). In early adolescence, significant predictors included informal house type (β = 0.82; 95% CI [0.71;0.93]), caregiver alcohol use (β = 0.74; 95% CI [0.67;0.81]), exposure to violence (β = 0.73; 95% CI [0.67;0.78]), friend support (β=-0.61; 95% CI [-0.67;-0.55]), food insecurity (β = 0.51; 95% CI [0.46;0.56]), family support (β=-0.33; 95% CI [-0.37;-0.29]), and self-esteem (β=-0.33; 95% CI [-0.37;-0.29]).

conclusionThis study identifies key predictors of internalising symptoms in adolescents from high-risk context, focusing on caregiver variables and social connections. Maternal / Primary cargiver depression and caregiver unemployment in early childhood have lasting effects, highlighting the need for early intervention. In early adolescence, factors such as social environment and caregiver stability are crucial. These insights can inform targeted interventions and policies to support adolescent mental health in high-risk contexts.

Indexed as

DepressionAdolescentChildFemaleHumansLongitudinal StudiesMaleMothersRisk FactorsSouth AfricaYoung AdultAdolescents; internalising symptomsHigh-Risk contentLongitudinal study

Identifiers

PMID41670682
PMCPMC13424707

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