ArticleAnalytical and bioanalytical chemistry2026
Determination of selected gadolinium-based contrast agents in soil: method validation and application.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The increasing use of reclaimed water for agricultural irrigation raises concerns about the environmental accumulation of persistent contaminants, including gadolinium-based contrast agents (GBCAs). These compounds, widely used in medical imaging, are excreted unmetabolized and poorly removed by conventional wastewater treatment plants, leading to their release into aquatic environments and potential accumulation in soils and crops. In this study, a method was developed, validated, and applied-for the first time-for the determination of three commonly used GBCAs-gadoteric acid, gadoteridol, and gadobutrol-in clay soil. Quantification was achieved by ion chromatography coupled to inductively coupled plasma mass spectrometry (IC-ICP-MS). Suitable separation was accurately optimized using a mobile phase containing 30 mM EDTA and 20 mM NH
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