Evidence map›Paper›PMID 41670608›Full record

Trial reportJournal of child psychology and psychiatry, and allied disciplines2026

The randomized controlled trial Fast Track multilevel intervention for children with early-emerging conduct problems breaks intergenerational transmission of violence across three generations.

Laura Gorla, W Andrew Rothenberg, Jennifer Godwin, Conduct Problems Prevention Research Group

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of child psychology and psychiatry, and allied disciplines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01653535 (Multisite Prevention of Conduct Problems), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01653535 naactive not recruitingnot on this map

Multisite Prevention of Conduct Problems

TypeinterventionalSponsorDuke UniversityRan1991 to 2029Enrolled891ConditionsConduct Disorder, Anti-Social BehaviorArmsFast Track
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura GorlaCenter for Child and Family Policy, Duke University, Durham, NC, USA.ORCID 0000-0001-5939-3134
W Andrew RothenbergCenter for Child and Family Policy, Duke University, Durham, NC, USA.ORCID 0000-0002-1739-9041
Jennifer GodwinCenter for Child and Family Policy, Duke University, Durham, NC, USA.ORCID 0000-0003-1956-4917
Conduct Problems Prevention Research Group

Funding

TRANSLATION AND DISSEMINATION COREP30DA023026 · NIDA · DUKE UNIVERSITY · PI HOYLE, RICK · 2008 to 2023
$19.6M
Optimizing Prevention of Costly Adult OutcomesR01DA016903 · NIDA · DUKE UNIVERSITY · PI CROWLEY, DANIEL MAX, DODGE, KENNETH A · 2003 to 2019
$10.2M
Vulnerability to Drug Abuse:Pathways to RecoveryR01DA011301 · NIDA · DUKE UNIVERSITY · PI COSTELLO, ELIZABETH JANE · 1997 to 2015
$7.3M
Intervention Impacts on Child Wellbeing and Parenting across GenerationsR01HD093651 · NICHD · DUKE UNIVERSITY · PI KENNETH A DODGE, Jennifer E Lansford · 2017 to 2026
$6.1M
MULTISITE PREVENTION OF CONDUCT PROBLEMSR18MH048043 · NIMH · DUKE UNIVERSITY · PI DODGE, KENNETH A · 1990 to 2002
$5.8M
MULTISITE PREVENTION OF CONDUCT DISORDERSR18MH050951 · NIMH · UNIVERSITY OF WASHINGTON · PI MCMAHON, ROBERT J. · 1993 to 2002
$3.7M
MULTISITE PREVENTION OF CONDUCT DISORDERR18MH050952 · NIMH · VANDERBILT UNIVERSITY · PI PINDERHUGHES, ELLEN E · 1993 to 2002
$3.7M
MULTISITE PREVENTION OF CONDUCT DISORDERR18MH050953 · NIMH · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI BIERMAN, KAREN L · 1993 to 2002
$3.5M
ECONOMIC ANALYSIS OF THE FAST TRACK INTERVENTIONR01MH062988 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FOSTER, EDWARD MICHAEL · 2002 to 2007
$2.8M
Diseases of Despair in Young Adulthood: Risk, Resilience, and PreventionR01MH117559 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI COPELAND, WILLIAM · 2018 to 2021
$1.6M
Adolescent Drug Use: Development, Prevention, and PolicyK05DA015226 · NIDA · DUKE UNIVERSITY · PI DODGE, KENNETH A · 2002 to 2012
$1.2M
Emergence of Adolescent Substance Use Problems from the Externalizing SpectrumRC1DA028248 · NIDA · UNIVERSITY OF WASHINGTON · PI KING, KEVIN MICHAEL · 2009 to 2010
$857k
B. C. Children's Hospital Research InstituteCanada Foundation for InnovationNational Institute of Mental Health (NIMH) K05 MH00797National Institute of Mental Health (NIMH) K05 MH01027National Institute of Mental Health (NIMH) R18 MH48043National Institute of Mental Health (NIMH) R18 MH50951National Institute of Mental Health (NIMH) R18 MH50952National Institute of Mental Health (NIMH) R18 MH50953National Institute on Drug Abuse (NIDA) K05 DA15226National Institute on Drug Abuse (NIDA) R01 DA11301NICHD NIH HHS R01 HD093651NIDA NIH HHS K05 DA015226NIDA NIH HHS P30 DA023026NIDA NIH HHS R01 DA011301NIDA NIH HHS R01 DA016903NIDA NIH HHS R01 DA036523NIDA NIH HHS RC1 DA028248NIMH NIH HHS R01 MH062988NIMH NIH HHS R01 MH117559NIMH NIH HHS R18 MH048043NIMH NIH HHS R18 MH050951NIMH NIH HHS R18 MH050952NIMH NIH HHS R18 MH050953The Center for Substance Abuse PreventionU.S. Department of Education S184U30002
6 · The paper itself

Abstract

backgroundDomestic violence mechanisms are frequently transmitted across generations, representing a global issue demanding particular attention. This study investigates the intergenerational transmission of intimate partner violence (IPV) and parent-to-child violence (PCV) and whether participating in a multilevel preventive intervention (Fast Track) breaks this transmission.

methodsIn high-risk elementary schools located in the United States, children considered at high risk for aggressive behavior based on teachers' and parents' screen scores were assigned to either a 10-year intervention or a control group based on their school. The Fast Track trial was registered at clinicaltrials.gov (NCT01653535) and was focused on parenting practices and children's intrapersonal, interpersonal, and academic skills. From the original 891 children, 374 participants with children aged less than 18 years (n = 191 intervention group, n = 183 control group) reported at age 34 their experience with domestic violence and their children's psychological adjustment.

resultsThe intergenerational mediating pathway from high IPV in the first generation to high PCV in the second generation to greater total mental health difficulties in the third generation was statistically significant in the control group but not in the intervention group.

conclusionsIPV was intergenerationally transmitted by influencing PCV, with a negative effect on the third generation's mental health. Nevertheless, participation in the Fast Track intervention disrupted this cycle. These findings suggest the importance of policies to support preventive childhood interventions.

Indexed as

Conduct DisorderDomestic ViolenceIntimate Partner ViolenceParentingPsychosocial InterventionAdolescentChildFemaleHumansMaleintergenerationalinterventionintimate partner violenceparent‐to‐child violence

Identifiers

PMID41670608
PMCPMC13182863

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.