Evidence map›Paper›PMID 41670095›Full record

ArticleEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2026

Trends and spatial distribution of pediatric second-dose COVID-19 vaccination coverage: a temporal analysis, Brazil, 2022-2023.

Kassya Fernanda Freire Lima, Marta Silva de Santana, Girlane Caroline Pereira Santos, Pablo Nascimento Cruz, Thaysa Goes Trinta Abreu, Lívia Maia Pascoal, Rosângela Fernandes Lucena Batista, Rosilda Silva Dias, Bruno Luciano Carneiro Alves de Oliveira

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Article in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Kassya Fernanda Freire LimaUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0009-0005-0032-3525
Marta Silva de SantanaUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0000-0001-8263-3490
Girlane Caroline Pereira SantosUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0009-0003-6203-8143
Pablo Nascimento CruzUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0000-0003-1010-0817
Thaysa Goes Trinta AbreuUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0009-0002-3426-4584
Lívia Maia PascoalUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0000-0003-0876-3996
Rosângela Fernandes Lucena BatistaUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0000-0002-1529-0165
Rosilda Silva DiasUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0000-0002-7969-9613
Bruno Luciano Carneiro Alves de OliveiraUniversidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brazil.ORCID http://orcid.org/0000-0001-8053-7972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the trend and spatial distribution of pediatric second-dose COVID-19 vaccination coverage among children aged 5 to 11 years in Brazil, in 2022 and 2023.

methodsThis was a time series analysis study using vaccination and target population data extracted from the Ministry of Health Vacinômetro platform. The second-dose coverage trend was estimated by joinpoint regression (segmented regression), while spatial distribution was analyzed using choropleth maps to identify regional variations between the Brazilian states.

resultsAverage monthly percentage change (AMPC) in vaccination coverage in Brazil as a whole remained stable during the period (AMPC -8.30%), with significant geographical heterogeneity. The Northern region (AMPC 5.76%) had a rising trend, in particular in the states of Acre (AMPC 23.42%) and Amazonas (AMPC 18.26%). Falling trends were observed in the Southeast region (AMPC -8.30%) as well as in specific states, such as Mato Grosso do Sul (AMPC -4.74%), Pará (AMPC -4.71%) and Rio de Janeiro (AMPC -4.27%). Fourteen states (51.9%) had a stable trend. The time series revealed initial increase in 2022, followed by deceleration and stabilization in 2023.

conclusionA significant and uneven variation in pediatric second-dose COVID-19 vaccination coverage was observed between 2022 and 2023. The results highlight the urgent need for targeted strategies to increase vaccination adherence, especially in areas with lower coverage.

Indexed as

COVID-19COVID-19 VaccinesVaccinationVaccination CoverageBrazilChildChild, PreschoolHumansSpatio-Temporal AnalysisTime FactorsCOVID-19 Vaccines

Identifiers

PMID41670095
PMCPMC12948298

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.