Evidence map›Paper›PMID 41670080›Full record

ArticleCadernos de saude publica2026

[Temporal and spatial heterogeneities of childhood vaccination coverage in Brazilian state capitals: a methodological proposal using an applied and expected dose ratio].

Mateus Henrique Silva Alves, Orozimbo Henriques Campos Neto, Karina Cardoso Meira, Isabel Silva Mitraud Ruas, Taynãna César Simões

Abstract readEnglish Abstract
In one paragraph

Article in Cadernos de saude publica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mateus Henrique Silva AlvesUniversidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0009-0002-8030-0574
Orozimbo Henriques Campos NetoInstituto de Educação Continuada, Pontifícia Universidade Católica de Minas Gerais, Contagem, Brasil.ORCID 0000-0001-6415-3709
Karina Cardoso MeiraDepartamento de Ciências Farmacêuticas, Universidade Federal de São Paulo, São Paulo, Brasil.ORCID 0000-0002-1722-5703
Isabel Silva Mitraud RuasUniversidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0009-0002-7793-6213
Taynãna César SimõesInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brasil.ORCID 0000-0002-5849-343X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to analyze vaccination coverage temporal and spatial heterogeneities in the basic children schedule in the Brazilian Unified National Health System (SUS) in state capitals and macroregions from 2010 to 2021 by a new monitoring indicator. This is an ecological study at the level of Brazilian capitals and year of registration of doses. An indicator based on the ratio between applied doses and the minimum expected number of doses (i.e., the recommended vaccination coverage in the complete basic vaccination schedule for children: BCG, hepatitis A and B, meningococcal conjugate C and its booster, pentavalent, pneumococcal 10-valent and its booster, poliomyelitis and its booster, human rotavirus, triple bacterial, and the first and second triple viral doses) was proposed. Dose ratios were temporally and spatially analyzed by generalized additive and conditional autoregressive models. This study found a significant drop in vaccination coverage for all immunobiologicals from 2015 onward. The coverage of most vaccines remained below the minimum targets of the Brazilian Ministry of Health. This study also observed differences in reduction magnitude (greater in Northern and Northeastern capitals in recent years, particularly during the COVID-19 pandemic). The proposed indicator facilitated statistical treatment, using only an information system and the recommended goals and making it possible to assess significant vaccination drops over time, with differences between capitals and macroregions. This study found priority regions for Brazilian National Immunization Program actions, such as intensifying and diversifying immunization campaigns to achieve the past high vaccination coverage.

Indexed as

Immunization ProgramsVaccinationVaccination CoverageBrazilChild, PreschoolHumansImmunization ScheduleInfantNational Health ProgramsSpatio-Temporal Analysis

Identifiers

PMID41670080
PMCPMC12884589

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.