Evidence map›Paper›PMID 41669989›Full record

Trial reportCancer2026

Impact of a web-based breast cancer surgery decision aid on knowledge and perceptions of feeling informed in clinics that care for socioeconomically disadvantaged patients: An Alliance Clinical Trial (A231701CD).

Jessica R Schumacher, Bret M Hanlon, David Zahrieh, Paul J Rathouz, Jennifer L Tucholka, Grace McKinney, Angelina D Tan, Catherine R Breuer, Lisa Bailey, Anna M Higham and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Providing information to prepare breast cancer patients for their surgical consultation: barriers and recommendations (an analysis from Alliance A231701CD).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jessica R SchumacherUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Bret M HanlonUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-4517-1204
David ZahriehAlliance Statistics and Data Management Center, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-0529-5146
Paul J RathouzUniversity of Texas at Austin Dell Medical School, Austin, Texas, USA.
Jennifer L TucholkaUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Grace McKinneyUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Angelina D TanAlliance Statistics and Data Management Center, Mayo Clinic, Rochester, Minnesota, USA.
Catherine R BreuerUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Lisa BaileyBay Area Tumor Institute, Oakland, California, USA.
Anna M HighamCarle Cancer Center, Urbana, Illinois, USA.
Julie S WecslerStroger Hospital of Cook County, Chicago, Illinois, USA.
Alicia ArnoldAugusta University Health, Augusta, Georgia, USA.ORCID https://orcid.org/0000-0001-9549-6296
Anthony J FroixHawaii NCORP, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Scott DullMontana Cancer Consortium NCORP, Billings Clinic, Billings, Montana, USA.
Andrea M AbbottMedical University of South Carolina, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0002-4817-8671
Stephanie G FineUniversity of New Mexico, Albuquerque, New Mexico, USA.
Kandace P McGuireVirginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, USA.
Anna S SeydelMarshfield Clinic, Marshfield, Wisconsin, USA.
Patricia McNamaraAlliance Statistics and Data Management Center, Mayo Clinic, Rochester, Minnesota, USA.
Selina ChowAlliance Protocol Operations Office, University of Chicago, Chicago, Illinois, USA.
Heather B NeumanUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-7462-8333

Funding

Collaborations and NCORP Collective ManagementUG1CA189823 · NCI · MAYO CLINIC ROCHESTER · PI Evanthia Galanis, Olwen Hahn · 2014 to 2026
$120.6M
AHRQ HHS R01 HS025194AHRQ HHS R01HS025194NCI NIH HHS UG1 CA189823NCI NIH HHS UG1CA189823
6 · The paper itself

Abstract

objectiveTo test the effectiveness of a surgical web-based decision aid (DA) in improving knowledge. SUMMARY OF BACKGROUND DATA: DAs support decision making by providing information about the options.

methodsA stepped wedge trial was conducted in 10 National Cancer Institute Community Oncology Research Program clinics (Alliance for Clinical Trials in Oncology). Clinics were randomized to time of transition from usual care (UC) to delivery of a web-based DA. Patients with stage 0 through 3 breast cancer being considered for surgery were enrolled. Knowledge (primary outcome) was measured using the Breast Cancer Surgery Decision Quality Instrument and patients were asked, "How informed do you feel?" Intervention effects were tested with linear mixed-effects models, accounting for surgeon and clinic-level clustering, time, and enrollment after COVID. Additional models controlled for demographics.

resultsA total of 44% of DA arm patients reviewed the DA and 58% in UC arm reported reviewing "any information." Being in the DA arm versus UC was not associated with knowledge. However, "review of information" was associated with higher knowledge. In addition, non-White race and lower education were associated with lower knowledge. The DA arm was associated with higher perceptions of feeling informed (parameter estimate 1.36; 95% CI, 0.18-2.55; p = .02); this persisted even when controlling for review of information or demographics.

conclusionImproved knowledge was not demonstrate with a web-based DA versus UC. Interestingly, the DA was associated with a higher likelihood of feeling informed. Future research will explore the discrepancy between patients feeling informed but having low knowledge, especially for disadvantaged patients.

trial registrationClinicalTrials.gov Identifier: NCT0376600.

Indexed as

Breast NeoplasmsDecision Support TechniquesHealth Knowledge, Attitudes, PracticeAdultAgedDecision MakingFemaleHumansInternetInternet-Based InterventionMastectomyMiddle AgedPatient Education as TopicVulnerable Populationsbreast cancerdecision aidengagementknowledgesocioeconomic disadvantagesurgery

Identifiers

PMID41669989
PMCPMC12892235

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.