Evidence map›Paper›PMID 41669962›Full record

ArticleJournal of the American Heart Association2026

Clinical Implications of Left Atrial and Ventricular Reverse Remodeling After Atrial Fibrillation Ablation in Patients With Systolic Dysfunction.

Masato Okada, Nobuaki Tanaka, Yasushi Koyama, Koji Tanaka, Yuko Hirao, Naoko Miyazaki, Kohei Iwasa, Heitaro Watanabe, Yoshitaka Iwanaga, Atsunori Okamura and 3 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Masato OkadaCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0002-3190-7313
Nobuaki TanakaCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0002-8324-1728
Yasushi KoyamaCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0001-6514-6869
Koji TanakaCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0002-2441-6364
Yuko HiraoCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0002-2628-5601
Naoko MiyazakiCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0009-0009-5964-1818
Kohei IwasaCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0001-7766-6896
Heitaro WatanabeCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.
Yoshitaka IwanagaCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0002-1391-2864
Atsunori OkamuraCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0003-0934-1955
Katsuomi IwakuraCardiovascular Center Sakurabashi Watanabe Advanced Healthcare Hospital Osaka Japan.ORCID 0000-0001-6617-1521
Koichi InoueCardiovascular Division National Hospital Organization Osaka National Hospital Osaka Japan.ORCID 0000-0002-8389-549X
Yasushi SakataDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0002-5618-4721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation of atrial fibrillation (AF) is an effective treatment to achieve left atrial (LA) and left ventricular (LV) reverse remodeling in patients with systolic dysfunction. However, the relationship between LA and LV reverse remodeling (LARR and LVRR) and their clinical implications remains unclear.

methodsAmong 5287 consecutive patients undergoing first-time AF ablation, 620 with baseline LV ejection fraction <50% were evaluated. They underwent multidetector computed tomography at baseline and 3 months after ablation. LARR and LVRR were defined as ≥15% reductions in the LA and LV end-systolic volume, respectively. The relationship between LARR and LVRR and their impact on clinical outcomes was investigated.

resultsAF ablation reduced the LA and LV end-systolic volumes, with reduction rates of 24%±16% and 39%±24%, respectively (r=0.54,

conclusionsLARR and LVRR were moderately correlated after AF ablation in patients with systolic dysfunction. Their combined assessment delineated distinct postablation trajectories and may improve individual risk stratification.

Indexed as

Atrial FibrillationAtrial Function, LeftAtrial RemodelingCatheter AblationVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingAgedFemaleHeart AtriaHumansMaleMiddle AgedMultidetector Computed TomographyRecurrenceRetrospective Studiesatrial fibrillationcatheter ablationoutcomesreverse remodeling

Identifiers

PMID41669962
PMCPMC13055692

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.