ArticleJournal of the American Heart Association2026
Prevalence and Trends in Cardiovascular Risk Factors Among Middle-Aged South Asian Adults Compared With Other Racial and Ethnic Groups in the United States: A Longitudinal Analysis of 2 Cohort Studies.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Non-HDL Cholesterol as a Predictor of Coronary Atherosclerosis in South Asians: A Narrative Review.Current atherosclerosis reports · 2026Review
- The Canadian multi-ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Observational
- Combined assessment of carotid intima-media thickness and epicardial fat thickness for cardiovascular risk stratification in asymptomatic South Indian adults.Frontiers in cardiovascular medicine · 2026Article
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10 authors.
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Abstract
backgroundPeople of South Asian background have a high burden of atherosclerotic cardiovascular disease (ASCVD). Few studies have examined if US South Asian individuals develop atherosclerotic cardiovascular disease risk factors at younger ages compared with other racial and ethnic groups.
methodsLongitudinal data from all eligible participants (ie, those aged between 45 and 55 years at time of the baseline examination) in the MASALA (Mediators of Atherosclerosis in South Asians Living in America) and the MESA (Multi-Ethnic Study of Atherosclerosis) cohort studies were combined. Data from all available examination visits (2010-2018 in MASALA and 2000-2018 in MESA) were used to estimate prevalence and change in prevalence of clinical and behavioral risk factors at ages 45 and 55 years for each racial and ethnic group and by gender.
resultsAt age 45 years, South Asian individuals had the highest prevalence of prediabetes and hypertension compared with White, Chinese, and Hispanic individuals. South Asian men had a higher dyslipidemia prevalence than White, Chinese, and Black men, while South Asian women had a higher prevalence than Chinese and Black women. At age 55 years, South Asian adults had the highest estimated hazard probability of diabetes among all racial and ethnic groups. At an increased age, clinical risk factor prevalence increased in all racial and ethnic groups, diet quality improved, and the prevalence of no leisure-time exercise decreased (ie, exercise improved).
conclusionsSignificant differences in risk factor prevalence were observed in South Asian adults compared with other US racial and ethnic groups at age 45 years. Understanding trends in cardiovascular risk and protective factors across the life course can help improve prevention and treatment strategies.
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