Evidence map›Paper›PMID 41669695›Full record

ArticleFrontiers in microbiology2025

Comparative analysis of cecal microbiota and metabolites in relation to growth performance of Tibetan and Hu sheep.

Feifei Yang, Lei Yang, Jinping Shi, Zhixiong Tang, Quanlu Meng, Zhengwu Pi, Haoke Li, Ting Liu, Changji Zhang, Shuru Cheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Phenological Changes in the Fecal Microbiota ofAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Feifei YangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Lei YangDingxi Vocational and Technical College, Dingxi, China.
Jinping ShiSchool of Animal Science and Technology, Ningxia University, Yinchuan, China.
Zhixiong TangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Quanlu MengCollege of Biological and Architectural Engineering, Baoji Vocational and Technical College, Baoji, China.
Zhengwu PiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Haoke LiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Ting LiuCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Changji ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Shuru ChengCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gastrointestinal microbiota play a crucial role in the growth and development of sheep. However, most existing studies have focused on the rumen microbiota, while comparatively little attention has been given to the cecum-the primary site of hindgut fermentation-and its metabolic functions. To investigate the potential influence of cecal microbiota and their metabolites on growth performance, we selected healthy male lambs of Tibetan and Hu sheep breeds at 3 months of age with similar body weights (19.55 ± 1.51 kg). After 3 months of feeding under identical conditions, the lambs were slaughtered, and cecal contents were analyzed using 16S rRNA gene sequencing and liquid chromatography-mass spectrometry (LC-MS). Results showed that Hu sheep exhibited significantly superior growth performance [body weight, average daily gain (ADG), and body size] compared to Tibetan sheep, accompanied by higher cecal concentrations of acetic, propionic, and butyric acids (

Indexed as

cecumintestinal microbiotametabolomicsproduction performancesheep

Identifiers

PMID41669695
PMCPMC12883762

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.