ArticleFrontiers in endocrinology2026
The effects of combined endurance training of different intensities and resistance training on bone mineral density, microstructure and mechanical properties of rats.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To explore the effects of different intensities of endurance training combined with resistance training on the bones of growing male rats, and to provide the optimal exercise plan for bone mineral accumulation in adolescents. Methods: Thirty 6-week-old male Sprague-Dawley rats were randomly divided into 5 groups: control (C), resistance training (R), low-intensity endurance + resistance (LR), moderate-intensity endurance + resistance (MR), and high-intensity interval + resistance (HR). After 8 weeks of exercise intervention, the bone mineral density, bone microstructure, bone mechanical properties and bone remodeling of rats were assessed. One-way analysis of variance (ANOVA) was used to test the results obtained by the detection methods. Results: The body weight of the exercise group was lower than that of the control group. The endurance and resistance training group (LR/MR/HR) had significantly higher bone mineral density than the control group ( Conclusion: Combined endurance and resistance training improved bone mineral density and mechanical strength in growing male rats, with moderate-intensity endurance training showing the most consistent improvements in bone microarchitecture.
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