ArticleQuantitative imaging in medicine and surgery2026
An applied study of blood oxygenation level-dependent and arterial spin labeling in early transplant renal function based on renal magnetic resonance angiography examination.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The early diagnosis of abnormalities in transplanted kidney function is crucial for timely intervention in transplant patients. Non-invasive tests play a key role in this process. This study aimed to explore the value of blood oxygenation level-dependent (BOLD) and arterial spin labeling (ASL) techniques, based on magnetic resonance angiography (MRA) examination, in evaluating early renal allograft function. Methods: A total of 68 consecutive renal transplant recipients were prospectively recruited. Of them, 10 were excluded due to magnetic resonance imaging (MRI) contraindications, hydronephrosis, and renal artery stenosis. Finally, 58 patients were included. The recipients were separated into three groups based on their estimated glomerular filtration rate (eGFR): Group A, recipients with good renal allograft function (eGFR ≥60 mL/min/1.73 m Results: A total of 58 patients (Group A, 29 cases; Group B, 18 cases; and Group C, 11 cases) were included in this study. Groups B and C presented with significantly decreased RBF as compared with Group A (259.74±47.52 Conclusions: BOLD and ASL can evaluate the different functional transplanted kidneys' oxygenation status and perfusion level. ASL demonstrates superior diagnostic efficacy compared to BOLD. BOLD combined with ASL has high value in identifying different transplanted kidney functions in the early stage.
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