Evidence map›Paper›PMID 41669435›Full record

ArticleQuantitative imaging in medicine and surgery2026

A novel approach for contrast enhancement in medical images based on quantum-inspired enhancement algorithm.

Heling Zhu, Junhao Su, Xiangyin Meng, Wenbo Li, Bo Yang, Jie Qiu

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Heling Zhu *Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Junhao Su *College of Information Science and Technology, Zhejiang Shuren University, Hangzhou, China.
Xiangyin MengDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wenbo LiDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bo YangDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jie QiuDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Computed tomography (CT) and magnetic resonance imaging (MRI) are essential in clinical diagnosis and treatment planning, but their images are often compromised by limited contrast and insufficient detail, reducing diagnostic clarity. Traditional enhancement methods-such as histogram equalization (HE) can improve visibility but may introduce noise, over-enhancement, or structural distortion. Quantum-inspired computational techniques have recently emerged as promising tools for nonlinear and adaptive image processing. Building on the quantum signal processing (QSP) framework, this study proposes a quantum-inspired enhancement (QIE) algorithm designed to improve medical image contrast while preserving structural details. Methods: We propose a QIE algorithm that embeds a three-pixel quantum-correlation system within a QSP framework. After normalizing grayscale values, each 3×3 neighborhood is mapped to superposition states; edge-sensitive basis states are selectively accumulated in four orientations to produce the enhanced output. The algorithm was evaluated using T2-weighted magnetic resonance (MR) brain images and CT lung images obtained from 10 different patients. Its performance was compared with four representative classical enhancement methods: HE, contrast-limited adaptive HE (CLAHE), fuzzy HE (FHE), and wavelet-based enhancement (WBE), employing quantitative metrics such as entropy, peak signal-to-noise ratio (PSNR), structural similarity index (SSIM), and contrast-to-noise ratio (CNR). Paired two-sided Results: QIE reached the highest mean entropy on both datasets (CT: 4.37±0.31; MR: 6.45±0.16) Conclusions: The proposed QIE algorithm demonstrates superior performance in enhancing the contrast and preserving the structural details of medical images. By leveraging quantum-inspired mechanisms, the algorithm shows potential for improving diagnostic accuracy and supporting clinical treatment planning. Future work will explore the application of this algorithm to other imaging modalities, investigate its effectiveness as a preprocessing step for commercial artificial intelligence (AI) models, and study the integration with actual quantum computing platforms.

Indexed as

computed tomography (CT)image processingmagnetic resonance imaging (MRI)Quantum-inspired enhancement (QIE)quantum signal processing

Identifiers

PMID41669435
PMCPMC12883455

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.