ArticleQuantitative imaging in medicine and surgery2026
Application of low-dose "one-stop" myocardial computed tomography perfusion imaging in coronary artery disease.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Calculation of Ejection Fraction Using Cardiac Computed Tomography: Clinical Evolution, Reliability, and Technological Challenges-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
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12 authors.
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Abstract
Background: Coronary computed tomography angiography (CCTA) has provided excellent anatomical detail for coronary artery disease (CAD), but does not provide hemodynamic assessment. The application of conventional computed tomography perfusion (CTP) combined with CCTA to address this issue has been found to increase the scan time, radiation dose, and contrast media (CM). This study aimed to evaluate the feasibility of the low-dose "one-stop" myocardial CTP as an innovative computed tomography (CT) examination that could comprehensively assess patients suspected of CAD in a single scan. Methods: Consecutive patients (n=94) with suspected CAD who underwent the 70 kV "one-stop" CTP and gender- and age-matched patients (n=62) who underwent conventional CCTA were included. The best enhanced CTP phase for coronary arteries was selected as the CCTA phase. The CM and effective dose (ED) were recorded. The image quality of the two groups was assessed. Patients who underwent CTP were divided into three groups [normal (0%, n=14), non-significant (1-49%, n=31), and significant stenosis (50-100%, n=49)] on the basis of degree of coronary stenosis. The cardiac function, myocardial strain, and myocardial blood flow (MBF) of each subgroup were analyzed. Results: Compared to the conventional CCTA protocol, the ED of "one-stop" CTP reduced by 44.5% (4.13±0.33 Conclusions: The advanced low-dose "one-stop" CTP protocol enables the simultaneous acquisition of coronary artery anatomy, ventricular function, myocardial strain, and hemodynamic information using low radiation dose and CM usage. This approach is beneficial for clinical decision-making and patient care in individuals with CAD.
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