Evidence map›Paper›PMID 41669378›Full record

ArticleAlgorithms2025

Synthesizing Explainability Across Multiple ML Models for Structured Data.

Emir Veledar, Lili Zhou, Omar Veledar, Hannah Gardener, Carolina M Gutierrez, Jose G Romano, Tatjana Rundek

Abstract read
In one paragraph

Article in Algorithms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emir VeledarDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1370, Miami, FL 33136, USA.ORCID 0000-0002-3831-5433
Lili ZhouDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1370, Miami, FL 33136, USA.ORCID 0000-0002-9684-5993
Omar VeledarBeevadoo e.U., Pfeifferhofweg 3b, 8045 Graz, Austria.ORCID 0000-0002-8302-7721
Hannah GardenerDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1370, Miami, FL 33136, USA.ORCID 0000-0003-1416-632X
Carolina M GutierrezDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1370, Miami, FL 33136, USA.ORCID 0000-0002-9879-3912
Jose G RomanoDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1370, Miami, FL 33136, USA.ORCID 0000-0003-3667-2792
Tatjana RundekDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1370, Miami, FL 33136, USA.ORCID 0000-0002-7115-9815

Funding

Miami Clinical and Translational Science InstituteUM1TR004556 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Olveen Carrasquillo, ERIN N KOBETZ · 2023 to 2026
$16.0M
Multi-morbidity 3-City Alzheimer's Disease EHR Study (M3AD Study)R56AG082167 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DESVARIEUX, MOISE, HRIPCSAK, GEORGE M · 2024 to 2024
$5.4M
Disparities in Transition of Care after Acute Stroke Hospitalization: The Transition of Care Stroke Disparity Study (TCSD-S)R01MD012467 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROMANO, JOSE G, RUNDEK, TATJANA · 2017 to 2021
$3.6M
Miami Clinical and Translational Science Institute K12 ProgramK12TR004555 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALESSIA FORNONI, Tatjana Rundek · 2023 to 2026
$3.0M
NCATS NIH HHS K12 TR004555NCATS NIH HHS UM1 TR004556NIA NIH HHS R56 AG082167NIMHD NIH HHS R01 MD012467
6 · The paper itself

Abstract

Explainable Machine Learning (XML) in high-stakes domains demands reproducible methods to aggregate feature importance across multiple models applied to the same structured dataset. We propose the Weighted Importance Score and Frequency Count (WISFC) framework, which combines importance magnitude and consistency by aggregating ranked outputs from diverse explainers. WISFC assigns a weighted score to each feature based on its rank and frequency across model-explainer pairs, providing a robust ensemble feature-importance ranking. Unlike simple consensus voting or ranking heuristics that are insufficient for capturing complex relationships among different explainer outputs, WISFC offers a more principled approach to reconciling and aggregating this information. By aggregating many "weak signals" from brute-force modeling runs, WISFC can surface a stronger consensus on which variables matter most. The framework is designed to be reproducible and generalizable, capable of taking important outputs from any set of machine-learning models and producing an aggregated ranking highlighting consistently important features. This approach acknowledges that any single model is a simplification of complex, multidimensional phenomena; using multiple diverse models, each optimized from a different perspective, WISFC systematically captures different facets of the problem space to create a more structured and comprehensive view. As a consequence, this study offers a useful strategy for researchers and practitioners who seek innovative ways of exploring complex systems, not by discovering entirely new variables but by introducing a novel mindset for systematically combining multiple modeling perspectives.

Indexed as

ensemble interpretabilityexplainable machine learningfeature-importance aggregationsmall-data settingsWISFC

Identifiers

PMID41669378
PMCPMC12885564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.