Evidence map›Paper›PMID 41669374›Full record

ArticleCase reports in hepatology2026

Exceptionally Long Recurrence-Free Survival in a Male Patient With Fibrolamellar Hepatocellular Carcinoma.

Elizabeth C Townsend, Disha Sharma, Harish Gopalakrishna, Maria Mironova, David E Kleiner, Theo Heller

Abstract read
In one paragraph

Article in Case reports in hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth C TownsendMedical Scientist Training Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA, uwm.edu.ORCID https://orcid.org/0000-0003-3102-8033
Disha SharmaDepartment of Gastroenterology, University of Maryland Medical Center, Baltimore, Maryland, USA, umaryland.edu.ORCID https://orcid.org/0000-0002-9352-625X
Harish GopalakrishnaLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA, nih.gov.ORCID https://orcid.org/0000-0003-3175-4983
Maria MironovaLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA, nih.gov.ORCID https://orcid.org/0000-0002-9783-097X
David E KleinerDepartment of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA, nih.gov.ORCID https://orcid.org/0000-0003-3442-4453
Theo HellerLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA, nih.gov.ORCID https://orcid.org/0000-0002-2643-6289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrolamellar hepatocellular carcinoma (FLHCC) accounts for less than 1% of all primary liver cancers. Due to an absence of known risk factors, most individuals are diagnosed at advanced stages of disease. Subsequently, these tumors carry a 30%-50% mortality rate and a 33%-100% recurrence rate in those treated with curative intent. Here, we describe an incidental discovery of an FLHCC tumor in a young male patient, who following surgical resection has remained recurrence free for over 11 years. This exceptionally long recurrence-free survival highlights the advantage of early-stage detection, the benefit of complete tumor resection, and further underscores the importance of regular postresection cancer surveillance.

Identifiers

PMID41669374
PMCPMC12883663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.