ArticleFrontiers in medicine2026
Clinical characterization of
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
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Abstract
Background: Psittacosis is a zoonotic disease caused by Methods: tNGS was performed on the platform of Vision Medicals in patients with fever or respiratory infections from August 2024 to August 2025 in our hospital. The specimens included blood and bronchoalveolar lavage fluid (BALF). Results: Eight psittacosis patients were detected by tNGS and confirmed by real-time PCR. The median age of 8 patients was 69 years (range: 46-86 years). Five patients (62.5%) had a history of exposure to birds. Clinical symptoms included fever, cough, fatigue, headache and dyspnea. Patients exhibited normal or elevated white blood cell (WBC) counts with decreased lymphocyte counts. C-reactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) levels were significantly elevated. The majority of patients (87.5%, 7/8) developed hepatic dysfunction. Pulmonary lesions were multi-lobar, presenting as consolidation, ground glass opacities and air bronchogram signs, with pleural effusion occurred in some cases. Following confirmation of Conclusion: tNGS is a promising tool for rapidly detecting
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