Evidence map›Paper›PMID 41669307›Full record

ArticleAdvanced biomedical research2025

Efficacy of Flaxseed Oil in Treating Mild to Moderate Psoriasis Vulgaris Compared with Topical Betamethasone: A Randomized, Double-Blind, Clinical Trial.

Farshad Mohammadian Rasanan, Ali Ghobadi, Hoorieh Mohammadi Kenari, Mohammadreza Ghassemi, Roshanak Ghods, Maryam Taghavi Shirazi

Abstract read
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Article in Advanced biomedical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farshad Mohammadian RasananInstitute for Studies in Medical History, Persian and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ali GhobadiInstitute for Studies in Medical History, Persian and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
Hoorieh Mohammadi KenariInstitute for Studies in Medical History, Persian and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mohammadreza GhassemiDepartment of Dermatology, Rasool Akram Medical Complex Research Development Center, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Roshanak GhodsInstitute for Studies in Medical History, Persian and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
Maryam Taghavi ShiraziInstitute for Studies in Medical History, Persian and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Psoriasis vulgaris poses health challenges to humans. Despite notable progress in the understanding of disease pathogenesis and the availability of various treatment options, a definitive cure remains elusive. Given the various side effects and high treatment costs, many patients seek natural remedies. This study aimed to assess the effectiveness of novel topical flaxseed oil in individuals with mild to moderate plaque psoriasis. Materials and Methods: The outcomes of topical flaxseed oil were compared with those of betamethasone ointment in a two-arm parallel, randomized, controlled clinical trial involving 60 patients. The participants applied the medication as a thin layer to the skin lesions, massaging it twice a day for 4 weeks. Before and after the intervention, they were assessed using two standard questionnaires: the Psoriasis Area Severity Index (PASI) and the Dermatology Life Quality Index. Results: Statistical analysis showed that, after 4 weeks, flaxseed oil significantly decreased the PASI score (2.43 ± 1.83 vs. 5.85 ± 5.08, Conclusion: The outcomes suggest that topical flaxseed oil can be an effective complementary therapy for psoriasis vulgaris.

Indexed as

Flaxseed oilPersian medicinepsoriasistraditional medicine

Identifiers

PMID41669307
PMCPMC12885202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.