ArticleAdvanced biomedical research2025
Tuberculosis of the Cuboid Bone: An Unfamiliar Manifestation of a Familiar Disease.
Article in Advanced biomedical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This report discusses a patient with chronic ankle pain for 2 years. No respiratory symptoms were present, but her father had tuberculosis (TB) when she was four. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were elevated. Empirical antibiotic therapy was initiated. The viral panel test was negative, while the purified protein derivative (PPD) test showed >20 mm induration. Chest radiograph and computed tomography (CT) scan were normal. Ankle radiograph revealed hypodense areas, osteolytic changes, and soft tissue swelling in the cuboid bone. Magnetic resonance imaging (MRI) confirmed soft tissue signal in the cuboid bone. Biopsy showed non-caseating necrotizing granulomatous reaction. The polymerase chain reaction (PCR) and culture confirmed M. tuberculosis infection. Anti-TB treatment was initiated. Skeletal TB in peripheral bones is very rare. Early-stage diagnosis can be challenging due to various potential causes, leading to irreversible complications. Thus, a high index of clinical suspicion should always be maintained. Imaging findings may be suggestive but not confirmative.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.