Evidence map›Paper›PMID 41669122›Full record

ReviewAfrican health sciences2025

Uptake and rollout of the World Health Organization-endorsed technologies for Tuberculosis diagnosis in Africa: a literature review of international evidence 2007-2021.

Jean de Dieu Iragena, Esther Uwimaana, Derrick Semugenze, Kevin Komakech, Achilles Katamba, Anandi Martin, Moses Joloba, Willy Ssengooba

Abstract readReview
In one paragraph

Review in African health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jean de Dieu IragenaDepartment of Immunology and Molecular Biology, Makerere University College of Health Sciences, School of Biomedical Sciences Kampala, Uganda.
Esther UwimaanaMakerere University Lung Institute, Kampala, Uganda.
Derrick SemugenzeDepartment of Medical Microbiology, Makerere University College of Health Sciences Kampala, Uganda.
Kevin KomakechDepartment of Medical Microbiology, Makerere University College of Health Sciences Kampala, Uganda.
Achilles KatambaDepartment of Medicine, Makerere University School of Medicine, Clinical Epidemiology and Biostatistics Unit.
Anandi MartinUganda Implementation Research Consortium, Kampala, Uganda.
Moses JolobaDepartment of Immunology and Molecular Biology, Makerere University College of Health Sciences, School of Biomedical Sciences Kampala, Uganda.
Willy SsengoobaMakerere University Lung Institute, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The World Health Organization (WHO) has endorsed a range of diagnostic tuberculosis (TB) over the years. A little is documented about the uptake in the WHO African Region (WHO/FR). Objective: We assessed the uptake of the endorsed diagnostic technologies for tuberculosis through a literature review. Methods: We reviewed literature in French and English from PubMed, Google Scholar, and Embase for TB diagnostics endorsed by WHO between January 2007 and December 2017, extending to December 2021 for recent technologies. We included publications from the 47 countries in the WHO/AFR. Data were analyzed using PRISMA diagrams and STATA 14.0. Results: Out of 3,399 articles, 1,716 articles were screened, and 92 qualified for analysis. The majority of articles were on Xpert MTB/RIF (XPERT) 22 (47%), Line Probe Assay (LPA), 10 (21%), and Mycobacteria Growth Indicator Tube (MGIT) 9 (19%). For rollout, 11 (24%) of countries had publications on Lipoarabinomannan (LAM) and 16 (36%) on XPERT. The median years for uptake were 6 for MGIT, 5 for XPERT, and 2.5 for LPA. For the rollout, the median years for MGIT, LPA, and XPERT were 7, 6, and 5 respectively. Conclusion: Our study shows that the uptake and rollout are slow. Future studies should identify factors affecting rapid uptake and rollout.

Indexed as

TuberculosisAfricaHumansMycobacterium tuberculosisRapid Diagnostic TestsWorld Health Organizationliterature reviewTuberculosis (TB) diagnosisUptake and rolloutWorld Health Organization African Region (WHO/AFR)

Identifiers

PMID41669122
PMCPMC12883973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.