Evidence map›Paper›PMID 41669005›Full record

ArticleJournal of orthopaedic case reports2026

Outcomes of Clinico-radiologically Predetermined Patient-specific Multi-site Steroid Injection in Primary Frozen Shoulder: A Prospective Study.

Ayyappan V Nair, Maythilisharan Rambhojun, M S Bharath Bharadhwaj, Shruthi Baburaj, Nizaj Nasimudeen, Prince Shanavas Khan

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Article in Journal of orthopaedic case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ayyappan V NairDepartment of Orthopaedics, Manipal Whitefield Hospital, Bengaluru, Karnataka, India.
Maythilisharan RambhojunDepartment of Orthopaedics, Manipal Whitefield Hospital, Bengaluru, Karnataka, India.
M S Bharath BharadhwajDepartment of Orthopaedics, Manipal Whitefield Hospital, Bengaluru, Karnataka, India.
Shruthi BaburajDepartment of Orthopaedics, Manipal Whitefield Hospital, Bengaluru, Karnataka, India.
Nizaj NasimudeenDepartment of Orthopaedics, Apollo Adlux Hospital, Kochi, Kerala, India.
Prince Shanavas KhanDepartment of Orthopaedics, Apollo Adlux Hospital, Kochi, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Frozen shoulder (FS) is characterized by pain and progressive restriction of motion, with treatment aimed at pain relief, functional improvement, and shortening disease duration. While conservative management is preferred, the best non-surgical modality remains unclear due to heterogeneity in the literature. The current study is to determine the efficacy of patient-specific multi-site landmark-based steroid injection in combination with a standardized physiotherapy protocol followed at our center in the management of Fss. Materials and Methods: In this prospective study, 94 patients with primary FS, confirmed via ultrasound and X-ray, received intra-articular and multisite betamethasone injections (8 mg diluted in 8 mL of 2% lignocaine). A total of 5 mL was injected intra-articularly, while the remaining was divided among the areas of tenderness and inflammation pre-determined clinically or radiologically by ultrasound. Injections were performed by a single shoulder surgeon, followed by an 8-week physiotherapy protocol. Patients were assessed at 2, 4, 8- and 12-weeks using range of motion (ROM), Visual Analog Scale (VAS), American Shoulder and Elbow Scoring system (ASES), and Shoulder Pain and Disability Index scores. Results: Statistically significant improvements were observed: mean abduction increased from 124° to 173° (P = 0.001), forward flexion from 123° to 174° (P = 0.040), and external rotation from 26° to 55° (P = 0.009). The mean ASES score improved from 28.8 to 92.5 (P = 0.001), VAS decreased from 6.7 to 0.4, and internal rotation improved by 4 vertebral levels. Conclusion: The results of our study demonstrate that patient-specific multi-site steroid infiltration significantly reduces pain and improves ROM and clinical outcomes in FS patients.

Indexed as

adhesive capsulitisanterior approachbetamethasoneFrozen shoulderintra-articular steroid injection

Identifiers

PMID41669005
PMCPMC12884312

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