Evidence map›Paper›PMID 41668996›Full record

ReviewExperimental and therapeutic medicine2026

Exploring the roots of schizophrenia: Current research and future directions (Review).

Shuang Lv, Chunxia Luo

Abstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shuang LvDepartment of Psychiatry, Guangzhou Kangning Hospital (The Psychiatric Hospital of Guangzhou Civil Administration Bureau), Guangzhou, Guangdong 510430, P.R. China.
Chunxia LuoDepartment of Psychiatry, Guangzhou Kangning Hospital (The Psychiatric Hospital of Guangzhou Civil Administration Bureau), Guangzhou, Guangdong 510430, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mental health holds critical global significance. However, mental illness remains insufficiently acknowledged worldwide. The prevalence and economic impact of mental disorders continue to rise, contributing notably to increased disability rates. Schizophrenia, with a global lifetime prevalence of ~0.4%, is a leading cause of disability. Currently, revealing the pathological mechanisms of schizophrenia, exploring early objective diagnosis and individualized treatment prediction indicators, and developing more effective treatment technologies are still hotspots in research. Several studies highlight schizophrenia as a severe, multifactorial disorder that directly disrupts brain function and profoundly impacts daily life. This review provides an overview of recent advances in schizophrenia research, summarising current research on the mechanisms of its pathogenesis; both genetic and environmental factors exert a significant influence on schizophrenia. Furthermore, investigations into animal models for schizophrenia research aim to establish more precise models, which will facilitate further exploration of the disease's pathogenesis and therapeutic approaches.

Indexed as

disease modelmental healthpathogenesisschizophrenia

Identifiers

PMID41668996
PMCPMC12884140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.