ArticleGland surgery2026
Identifying risk factors for postoperative hypocalcemia in primary hyperparathyroidism: 12-year experience in a tertiary hospital.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hypocalcemia is the most common complication following parathyroidectomy (PTX) in patients with primary hyperparathyroidism (PHPT). With asymptomatic PHPT cases increasingly comprising a larger proportion of clinical presentations, the association between preoperative symptom status and postoperative hypocalcemia risk remains poorly defined. This study aimed to identify risk factors for hypocalcemia after PTX in symptomatic Methods: A retrospective analysis was performed on patients with primary PHPT who underwent PTX between July 2012 and August 2024. A total of 478 patients were included and categorized into two groups based on symptomatic status at admission. Data regarding demographics, surgical details, and laboratory parameters were collected. Univariate and multivariate analyses were performed to identify factors associated with postoperative hypocalcemia in PHPT patients. Results: Multivariate analysis revealed that the preoperative serum chloride/calcium (Cl/Ca) ratio [odds ratio (OR) =1.104; 95% confidence interval (CI): 1.025-1.190; P=0.009], alkaline phosphatase (OR =1.002; 95% CI: 1.001-1.003; P=0.001) and female gender (OR =0.257; 95% CI: 0.103-0.641; P=0.004) were statistically significant predictors of early postoperative hypocalcemia in the symptomatic group. In the asymptomatic group, age ≤60 years (OR =0.379; 95% CI: 0.161-0.894; P=0.03) and a higher preoperative serum Cl/Ca ratio (OR =1.335; 95% CI: 1.170-1.523; P<0.001) were identified as independent predictors of early postoperative hypocalcemia. Conclusions: This first stratification analysis of PHPT patients by symptomatic status identified the serum Ca/Cl ratio as a common, independent predictor of post-PTX hypocalcemia in both symptomatic and asymptomatic groups. Additionally, in symptomatic patients, alkaline phosphatase levels and female gender were associated with early hypocalcemia. Conversely, for asymptomatic patients, age ≤60 years emerged as a significant predictor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.