ArticleERJ open research2026
Predictors of COPD exacerbations differ between grades of airflow limitation.
Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
13 authors.
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Abstract
Background: History of exacerbations is a predictor of future exacerbations in COPD but there are also predictors that are independent of exacerbation history. However, it is unclear whether their relative contribution is consistent across different degrees of airflow limitation. Methods: This analysis used data from COMPASS, a prospective study in COPD. Baseline demographics, clinical history, spirometry and patient-reported outcomes were collected. Multivariable models were created to predict moderate or severe exacerbations in the 18 months after baseline. Covariates included forced expiratory volume in 1 s (FEV Results: At baseline there were 1696 patients; 89.6% males, 46.9% current smokers, mean±sd age of 65.4±7.5 years, post-bronchodilator FEV Conclusions: There are multiple predictors of COPD exacerbations, which differ between GOLD grades. Future predictive models for exacerbation risk should take this into account.
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