Evidence map›Paper›PMID 41668737›Full record

ArticleJournal of biomedical optics2026

Comparing multi- and single-exposure speckle contrast optical spectroscopy methods as estimators of blood flow in the diffuse regime.

Sean Aleman, Arnold D Estrada, Ashwin B Parthasarathy

Abstract readComparative Study
In one paragraph

Article in Journal of biomedical optics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sean AlemanUniversity of South Florida, Department of Medical Engineering, Tampa, Florida, United States.
Arnold D EstradaSPKL, LLC, Tampa, Florida, United States.
Ashwin B ParthasarathyUniversity of South Florida, Department of Electrical Engineering, Tampa, Florida, United States.ORCID https://orcid.org/0000-0003-2024-3432

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Speckle contrast optical spectroscopy (SCOS) and speckle plethysmography (SPG) are increasingly used to measure deep tissue blood flow from tissues. However these methods derive flow from measurements at a single exposure duration, which could introduce errors due to inefficient choice of a single integration time, changes in speckle averaging factors ( Aim: The aims are to compare and evaluate the robustness of single- and multi-exposure speckle contrast methods in estimating blood flow changes under experimental conditions such as Approach: Speckle visibility was simulated at 10,000 logarithmically spaced exposure durations (0.01 to 10 ms), incorporating Results: Multi-exposure speckle imaging (MESI) maintained Conclusions: MESI outperformed single-exposure approaches in estimating blood flow changes by reducing

Indexed as

Image Processing, Computer-AssistedLaser Speckle Contrast ImagingSpectrum AnalysisAlgorithmsBlood Flow VelocityComputer SimulationHumansPlethysmographyPulsatile Flowblood flowdiffuse correlation spectroscopydiffuse specklespecklespeckle contrast optical spectroscopyspeckle plethysmography

Identifiers

PMID41668737
PMCPMC12885091

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.