Evidence map›Paper›PMID 41668566›Full record

ArticleActa obstetricia et gynecologica Scandinavica2026

Induced abortion, miscarriage, and the risk of breast cancer-A registry-based study from Finland.

Sushmita Katuwal, Jaana Männistö, Maarit Niinimäki, Eero Pukkala, Oskari Heikinheimo

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sushmita KatuwalUnit of Health Sciences, Faculty of Social Medicine, Tampere University, Tampere, Finland.ORCID 0000-0002-3017-9430
Jaana MännistöDepartment of Obstetrics and Gynaecology, PEDEGO Research Unit, Medical Research Center Oulu, University Hospital of Oulu and University of Oulu, Oulu, Finland.ORCID 0000-0003-4466-619X
Maarit NiinimäkiDepartment of Obstetrics and Gynaecology, PEDEGO Research Unit, Medical Research Center Oulu, University Hospital of Oulu and University of Oulu, Oulu, Finland.ORCID 0000-0003-0927-0472
Eero PukkalaUnit of Health Sciences, Faculty of Social Medicine, Tampere University, Tampere, Finland.ORCID 0000-0001-9536-6440
Oskari HeikinheimoDepartment of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-8671-130X

Funding

Cancer Foundation FinlandHelsinki University Hospital
6 · The paper itself

Abstract

introductionThe potential effect of induced abortion and miscarriage on the risk of breast cancer has remained debated and has been a persistent source of misinformation. Many previous studies have been small and based on self-reported data. We assessed the associations of induced abortion and miscarriage with the risk of pre- and postmenopausal breast cancer using high-quality Finnish registry data. MATERIAL AND

methodsThis is a case-control study based on population-based registry data. It includes 31 687 women with breast cancer diagnosed between 1972 and 2021, and their 158 433 female population controls matched by birth year and parity. Data on induced abortions, miscarriages, deliveries, use of postmenopausal hormone therapy, socioeconomic status (SES), and occupation were collected from the Finnish national registries. Multivariate conditional logistic regression analysis was performed.

resultsThe odds ratio (OR) of breast cancer among women with a history of induced abortion as compared with women with no history of induced abortion was 1.01 (95% confidence interval [CI] 0.92-1.10) in premenopausal (age <50 years) and 0.96 (95% CI 0.87-1.07) in postmenopausal (≥50 years) women. The corresponding ORs for miscarriage were 1.02 (95% CI 0.89-1.16) and 0.93 (95% CI 0.80-1.09). The OR did not vary significantly by the number of induced abortions or miscarriages, nor by the age at the time of first induced abortion or miscarriage.

conclusionA history of induced abortion and miscarriage, regardless of their number or age of the woman, is not associated with an increased risk of subsequent pre- or postmenopausal breast cancer.

Indexed as

Abortion, InducedAbortion, SpontaneousBreast NeoplasmsAdultAgedCase-Control StudiesFemaleFinlandHumansMiddle AgedOdds RatioPostmenopausePregnancyRegistriesRisk Factorsand postmenopausal breast cancerearly pregnancyinduced abortionmiscarriagepremenopausal breast cancer

Identifiers

PMID41668566
PMCPMC13140503

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.