Evidence map›Paper›PMID 41668188›Full record

Trial reportBMC complementary medicine and therapies2026

Yoga intervention on the fatigue-pain-sleep disturbance symptom cluster for breast cancer patients receiving adjuvant chemotherapy: a pilot randomized controlled trial.

Yishu Qi, Ying Cao, Yanhong Deng, Xing Ma, Dorothy Ngo Sheung Chan, Cho Lee Wong, Yao Guo

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yishu QiThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., R824 Esther Lee Building, Shatin, N.T., Hong Kong SAR, China.
Ying CaoBreast Disease Center, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Yanhong DengBreast Disease Center, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Xing MaThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., R824 Esther Lee Building, Shatin, N.T., Hong Kong SAR, China.
Dorothy Ngo Sheung ChanThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., R824 Esther Lee Building, Shatin, N.T., Hong Kong SAR, China.
Cho Lee Wong *The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., R824 Esther Lee Building, Shatin, N.T., Hong Kong SAR, China. jojowong@cuhk.edu.hk.
Yao Guo *Breast Disease Center, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ndyfy02758@ncu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe fatigue-pain-sleep disturbance symptom cluster is a common and notable issue negatively impacting breast cancer patients receiving adjuvant chemotherapy. Yoga is a promising strategy for symptom cluster management. This study aimed to examine the feasibility, acceptability, and preliminary effects of yoga intervention on the fatigue-pain-sleep disturbance symptom cluster in breast cancer patients receiving adjuvant chemotherapy to explore its effect on alleviating patients’ symptom burden.

methodsIn a parallel-group pilot randomized controlled trial, 30 participants were randomly assigned to the intervention group or the control group. The participants in the control group received usual care, while those in the intervention group received yoga intervention and usual care. Feasibility was assessed using eligibility rate, recruitment rate, retention rate, adherence rate, and session attendance rate. Acceptability was assessed using a satisfaction scale and open-ended questions. The feasibility and acceptability of the intervention were evaluated post-intervention. Preliminary effects were assessed at baseline, post-intervention, and one-month follow-up.

resultsThirty participants were recruited, with a recruitment rate of 55.6%. Two participants dropped out of the study, and ten participants in the intervention group completed all intervention sessions, with a retention rate of 93.3% and a session attendance rate of 91.4%, showing high feasibility. 92.9% of participants expressed total satisfaction with the intervention, showing high acceptability. The yoga intervention achieved statistically significant post-intervention effects on the symptom cluster severity (P = 0.042), depression (P = 0.045), and health-related quality of life (P = 0.006) in breast cancer patients receiving adjuvant chemotherapy. No adverse event was reported.

conclusionsThis pilot study supports the feasibility and acceptability of yoga intervention for breast cancer patients receiving adjuvant chemotherapy. The results suggest that yoga intervention has potentially positive effects on the management of the fatigue-pain-sleep disturbance symptom cluster and related outcomes. Future research with a larger sample size is warranted to examine the long-term effects of yoga intervention.

trial registrationThe study was registered on the Chinese Clinical Trial Registry ( www.chictr.org.cn ), and trial registration number ChiCTR2400081863. The registration date was 14/03/2024.

Indexed as

Breast NeoplasmsFatiguePainSleep Wake DisordersYogaAdultChemotherapy, AdjuvantFemaleHumansMiddle AgedPilot ProjectsBreast cancerChemotherapyPilot studyRandomized controlled trialSymptom managementYoga

Identifiers

PMID41668188
PMCPMC12990628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.