Evidence map›Paper›PMID 41668186›Full record

Trial reportTrials2026

Recruiting people living with mild cognitive impairment into a fall prevention trial.

Elissa Burton, Nicola T Lautenschlager, Kathryn A Ellis, Anne-Marie Hill, Meggen Lowry, Rachael Moorin, Joanne McVeigh, Angela Jacques, Kirk I Erickson, Joel Tate and 5 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elissa BurtonCurtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia. E.Burton@curtin.edu.au.ORCID http://orcid.org/0000-0001-6470-8305
Nicola T LautenschlagerDepartment of Psychiatry, The University of Melbourne, Melbourne, Australia.
Kathryn A EllisDepartment of Psychiatry, The University of Melbourne, Melbourne, Australia.
Anne-Marie HillSchool of Allied Health, Western Australian Centre for Health and Ageing, The University of Western Australia, Perth, WA, Australia.
Meggen LowryNext Step Health, Brisbane, QLD, Australia.
Rachael MoorinCurtin School of Population Health, Faculty of Health Sciences, Curtin University, Perth, Australia.
Joanne McVeighCurtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia.
Angela JacquesCurtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia.
Kirk I EricksonAdventHealth Research Institute, Neuroscience, Orlando, FL, USA.
Joel TateDepartment of Rehabilitation and Aged Care, Armadale Health Service, Perth, Australia.
Sarah BernardCurtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia.
Carolyn F OrrCognitive Clinic, Royal Perth Hospital, Perth, Australia.
Luke BongiasciaPhysiotherapy Department, Adult Community and Allied Health Directorate, Rockingham Peel Group, Rockingham, Australia.
Melanie L ClarkNeurosciences Unit, North Metropolitan Health Service Mental Health, Public Health and Dental Services, Perth, Australia.
Keith D HillRehabilitation, Ageing and Independent Living (RAIL) Research Centre, School of Primary and Allied Health Care, Monash University, Melbourne, Australia.

Funding

National Health and Medical Research Council GNT1174739
6 · The paper itself

Abstract

backgroundPeople with mild cognitive impairment (MCI) fall as often as people living with early dementia. Yet, few trials have investigated the effectiveness of fall prevention interventions for people with MCI. Recruitment of specific populations into long-term trials can be challenging, and to assist future studies, it is necessary to better understand more about trial recruitment. This study outlines the recruitment of people with MCI into the Balance on the Brain trial. This was a single-blind randomised controlled trial based in the Perth Metropolitan Area, which included people living with MCI in the community, aged 50 or over, and who were self-reported to not be meeting the Australian physical activity guidelines. The multi-modal exercise intervention was for 6 months, and all participants were followed up monthly for 12 months. A sample size of 396 was calculated to meet the requirements for the falls primary outcome (212 participants for the balance primary outcome).

methodsEleven recruitment strategies were used across the 36-month recruitment (January 2021 through to December 2023). Some recruitment strategies had costs, and these are also outlined.

resultsA total of 780 potential participants were initially prescreened, 258 completed full REDCap DISCUSSION: Recruiting people with MCI can be difficult, exacerbated in this study by the concurrent COVID-19 pandemic. Less restrictive inclusion criteria and multisite recruitment may provide greater success. TRIALS REGISTRATION: Australian New Zealand Clinical Trials Registry (ANZCTRN) ACTRN12620001037998. Registered on 12 October 2020.

Indexed as

Accidental FallsCognitive DysfunctionExercise TherapyPatient SelectionAgedAged, 80 and overAustraliaFemaleHumansMaleMiddle AgedPostural BalanceSingle-Blind MethodFall preventionFallsMild cognitive impairmentRandomised controlled trialRecruitment

Identifiers

PMID41668186
PMCPMC12918016

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.