SynthesisAesthetic plastic surgery2026
Safety and Efficacy of Chin Enhancement and Facial Contouring with Two-Three-Point Injection Technique: A Systematic Review and Meta-Analysis.
Synthesis in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
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Abstract
BACKGROUND AND
aimThe present study aimed to evaluate the effectiveness of the two-three-point injection technique using hyaluronic acid fillers to increase chin volume.
methodThe present study included three RCT and three cohort studies of international databases, PubMed, Scopus, Web of Science, and Embase using relevant keywords until June 2025. The statistical analysis was performed with Stata/MP.v17 as fixed or random effect models.
resultsThe GAIS responder rate for chin enhancement of HA filler with two-three-point injection technique was 94% (ES: 0.94; P < 0.001; 95% CI 0.92, 0.97). Common ISRs were firmness (ES: 91%; 95% CI 88-94%) and swelling (ES: 87%; 95% CI 84-90%). The overall rate of adverse events was estimated to be 7.92% (ES: 7.92%; 95% CI 6.31-9.53%).
conclusionHigh efficacy and acceptable safety were evident for the two-three-point injection technique for HA filler injection for the chin enhancement. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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