ArticleCommunications medicine2026
Assessments of social vulnerability on central nervous system cancer disparities in the United States.
Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Individual and community-level associations of social determinants with pituitary adenoma disparities in the US.Journal of neuro-oncology · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrior investigations of the impact of social determinants of health (SDH) on people with primary central nervous system cancers (PCNSC) have considered limited SDH-factors and pathologies. This study examines how the Social Vulnerability Index (SVI) influences disparities in outcome for people with PCNSC across the United States (US).
methodsThis population-based retrospective cohort study assessed adults with PCNSC between 1975-2017 from the Surveillance-Epidemiology-End Results database, categorized using the Central Brain-Tumor-Registry of the US (CBTRUS) classifications. SDH-vulnerability/SVI scores were assigned to patients' county-of-residence based on 15 SDH-factors of socioeconomic status (SES), proportions using a minority language (ML), household composition (HC), and infrastructure/housing-transportation (HT) characteristics, plus an overall composite of these four themes. Survival and logistic regressions were obtained for survival period and multimodal treatment receipt across all PCNSC-patients based on their SVI-scores/SDH-vulnerability.
resultsAcross 116,373 PCNSC-patients (64,841 [55.7%] male; 92,476 [79.5%] non-Hispanic white race-ethnicity), increasing overall SDH-vulnerability is associated with relative mean survival period decreases between 22.12%-45.81% across 8/8 CBTRUS-classes, with the largest-magnitude effects among HC, HT, and SES-vulnerabilities. There are decreased odds of external beam radiation for 4/8 CBTRUS-classes (lowest-embryonal: OR, 0.87; 95%CI, 0.80-0.96) and surgery for 3/8 CBTRUS classes (lowest-oligodendroglial: OR 0.96; 95%CI 0.95-0.97). The largest-magnitude effects are among those using ML, followed by impact of HC and HT characteristics.
conclusionsSDH-vulnerability associates with worse survival and treatment effects for PCNSC patients. Some specific SDH more strongly influence disparity associations, so resources could be focused more on reducing these disparity drivers.
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Registered trials
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