Evidence map›Paper›PMID 41667727›Full record

SynthesisLangenbeck's archives of surgery2026

A systematic review and meta-analysis of subcutaneous onlay laparoscopic (SCOLA) approach for diastasis recti with or without mesh reinforcement.

Antonio Vitiello, Giovanna Berardi, Roberto Peltrini, Ruggero Lionetti, Vincenzo Pilone

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Rectus diastasis is not a single entity: phenotype-specific controversies in surgical management.Hernia : the journal of hernias and abdominal wall surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonio VitielloAdvanced Biomedical Sciences Department, Naples "Federico II" University, AOU "Federico II" - Via S. Pansini 5, Naples, 80131, Italy. antoniovitiello@hotmail.it.
Giovanna BerardiUniversity Hospital of Naples Federico II - Via S. Pansini 5, Naples, 80131, Italy.
Roberto PeltriniAdvanced Biomedical Sciences Department, Naples "Federico II" University, AOU "Federico II" - Via S. Pansini 5, Naples, 80131, Italy.
Ruggero LionettiUniversity Hospital of Naples Federico II - Via S. Pansini 5, Naples, 80131, Italy.
Vincenzo PilonePublic Health Department, Naples "Federico II" University, AOU "Federico II" - Via S. Pansini 5, Naples, 80131, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSCOLA represents a minimally invasive approach to combined diastasis recti and ventral hernia repair. This systematic review investigates the clinical efficacy and safety implications of mesh placement within this technique.

methodsWe followed PRISMA 2020 guidelines to search MEDLINE and EMBASE for studies reporting SCOLA outcomes in adult patients with midline hernias and/or diastasis recti. Additionally, we retrospectively identified six institutional SCOLA cases from January 2023 to March 2025. Extracted variables included patient demographics, hernia location and size, mesh use, follow-up duration, and rates of seroma, surgical-site infection (SSI), and recurrence. We calculated pooled complication rates and performed stratified meta-analyses, estimating risk ratios (RRs) and 95% confidence intervals (CIs) for mesh vs. no-mesh cohorts.

resultsSix eligible studies (1 prospective, 5 retrospective) involving 247 patients were included after systematic screening. Among all patients (99.2% laparoscopic SCOLA; mean defect size 2.77 cm; mean follow-up 9.5 months; mesh used in 72.5%), seroma occurred in 19.0% overall (21.8% vs. 11.8%; RR 1.85, 95% CI 0.88–3.89; p ≈ 0.104). Infections were seen only in the mesh group (5.0% vs. 0%; RR undefined, 95% CI 0.89–∞; p ≈ 0.058), and recurrence rates were low (1.7% vs. 0%; RR undefined, 95% CI 0.14–∞; p ≈ 0.318). Studies quality was moderate, limited by non-randomized designs and small observational cohorts.

conclusionsAvailable data suggest that SCOLA may achieve low recurrence rates, although high-quality evidence is limited. Mesh reinforcement may offer modest reduction in recurrence at the expense of an increased SSI risk. Seroma formation appears more influenced by extent of dissection than by mesh presence.

Indexed as

Hernia, VentralHerniorrhaphyLaparoscopySurgical MeshHumansPostoperative ComplicationsRecurrenceTreatment OutcomeDiastasis rectiMinimally invasive surgerySCOLASubcutaneous onlay laparoscopic approachVentral hernia

Identifiers

PMID41667727
PMCPMC12948846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.