Evidence map›Paper›PMID 41667713›Full record

ArticleCommunications engineering2026

In vivo acoustoelectric neural recording in mice enabled by ultrasound-induced frequency mixing.

Jean L Rintoul, Jonathan Howard, Patrycja Dzialecka, Xiaoqi Zhu, Nir Grossman

Abstract read
In one paragraph

Article in Communications engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jean L RintoulDepartment of Brain Sciences, Imperial College London, London, UK. j.rintoul19@alumni.imperial.ac.uk.ORCID http://orcid.org/0000-0002-1963-7023
Jonathan HowardDepartment of Brain Sciences, Imperial College London, London, UK.
Patrycja DzialeckaDepartment of Brain Sciences, Imperial College London, London, UK.ORCID http://orcid.org/0009-0005-0081-4682
Xiaoqi ZhuDepartment of Brain Sciences, Imperial College London, London, UK.
Nir GrossmanDepartment of Brain Sciences, Imperial College London, London, UK. nirg@imperial.ac.uk.ORCID http://orcid.org/0000-0003-2002-9049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a long-standing need in neuroscience for non-invasive methods that can record neural electrical activity with focal precision to diagnose brain disorders and interrogate circuit function. Here, we introduce acoustoelectric neural recording, which exploits ultrasound-induced frequency mixing to recover electrophysiological signals in vivo. Building on recent insights into the acoustoelectric interaction, we extend earlier work in cardiac tissue to demonstrate neural signal recovery in a living mouse brain. At the ultrasound focus, neural activity is shifted to frequencies near the acoustic carrier and can be retrieved by amplitude demodulation analogous to radio transmission. We further show that acoustoelectric neural recording is robust to artefacts and permits single-trial electrophysiological measurements. These results establish a pathway toward a real-time, portable, and non-invasive neural recording modality with the spatial precision of ultrasound.

Identifiers

PMID41667713
PMCPMC12920806

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.