Evidence map›Paper›PMID 41667708›Full record

ArticleNature biotechnology2026

Hemodynamics-driven magnetoelastic vascular grafts for stenosis diagnosis.

Guorui Chen, Tzuchun Chung, Zeyang Liu, Yan-Ruide Li, Kamryn Scott, Xun Zhao, Jarod Carol, Soomin Park, Yihao Zhou, Wi Jin Kim and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Advances in Wearable Bioimaging.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Guorui Chen *Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Tzuchun Chung *Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Zeyang LiuDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Yan-Ruide LiDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-9858-300X
Kamryn ScottDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Xun ZhaoDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-5543-0081
Jarod CarolDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Soomin ParkDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Yihao ZhouDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Wi Jin KimDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Xinyang GeDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Geoffrey P ColbyDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-3376-0933
Song LiDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA. songli@ucla.edu.ORCID http://orcid.org/0000-0002-4760-8828
Jun ChenDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA. jun.chen@ucla.edu.ORCID http://orcid.org/0000-0002-3439-0495

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Robert Damoiseaux · 1985 to 2026
$134.5M
Multimodal wireless electrical stimulation for tissue regenerationR01NS126918 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Song Li, John Rogers · 2022 to 2026
$2.4M
Magnetoelastic Vascular GraftsR01HL175135 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jun Chen · 2025 to 2026
$1.1M
A soft magnetoelastic microneedle patch for rapid skin cancer screeningR01CA287326 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jun Chen · 2024 to 2026
$1.1M
Small animal combined PET/CT systemS10OD026917 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHATZIIOANNOU, ARION XENOFON · 2020 to 2020
$750k
American Heart Association-American Stroke Association 23IPA1054908American Heart Association-American Stroke Association 23SCEFIA1157587American Heart Association-American Stroke Association 23TPA1141360NCI NIH HHS P30 CA016042NCI NIH HHS R01 CA287326NHLBI NIH HHS R01 HL175135NIH HHS S10 OD026917NINDS NIH HHS R01 NS126918
6 · The paper itself

Abstract

Conventional approaches for vascular graft stenosis diagnostics, including X-ray angiography, magnetic resonance imaging and Doppler ultrasound, although highly accurate, are cumbersome, used intermittently and often do not detect stenosis early enough, leading to diagnosis only after substantial narrowing. Here we report a magnetoelastic vascular graft (MVG) for post-implantation stenosis diagnosis that is hemodynamics-driven, biocompatible and waterproof. It enables wireless, real-time and continuous diagnosis of stenosis by converting arterial hemodynamics into high-fidelity electrical signals. The MVGs were scalably manufactured with customizable diameters and tested in vivo in the femoral arteries of rats and swine through microsurgical anastomosis. The anastomosed MVGs restored blood flow and identified the location and severity of induced stenosis through artificial intelligence-assisted analysis. Furthermore, a 4-month in vivo study in rats verified the stability and biocompatibility of the MVGs in the host, with no evident signs of an adverse immune response. The MVG is expected to advance existing vascular graft solutions and improve vascular disease management.

Indexed as

Blood Vessel ProsthesisGraft Occlusion, VascularHemodynamicsVascular GraftingAnimalsConstriction, PathologicFemoral ArteryRatsSwine

Identifiers

PMID41667708
PMCPMC13082911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.