Evidence map›Paper›PMID 41667695›Full record

ArticleSurgical endoscopy2026

Reported adverse events of the anchor prong clip: a MAUDE database analysis.

Peter Bhandari, Daryl Ramai, Reanay Berezovskiy, Celia Leone, Azizullah Beran, Sanjay M Salgado, Matthew A Grossman

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter BhandariDivision of Gastroenterology, Morristown Medical Center, Atlantic Health System, Morristown, NJ, USA. Peter.Bhandari@atlantichealth.org.ORCID http://orcid.org/0000-0003-3565-6205
Daryl RamaiDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, MA, USA.
Reanay BerezovskiyNew York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY, USA.
Celia LeoneDepartment of Internal Medicine, Morristown Medical Center, Atlantic Health System, Morristown, NJ, USA.
Azizullah BeranDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Sanjay M SalgadoDivision of Gastroenterology, Overlook Medical Center, Atlantic Health System, Summit, NJ, USA.
Matthew A GrossmanDivision of Gastroenterology, Morristown Medical Center, Atlantic Health System, Morristown, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe anchor-pronged clip has been widely adopted for closure of large defects, offering enhanced tensile strength and grasping ability. However, reported real-world device and patient adverse events are limited in literature. Our focus is to identify the most commonly reported adverse events, device issues, and their clinical implications.

methodsThe Food and Drug Administration (FDA) Manufacturer and User Facility Device Experience (MAUDE) database was analyzed from February 1, 2023 to December 31, 2024 to report post-marketing surveillance data on these anchor pronged clips.

resultsApproximately 135 reported cases with 187 device issues and 30 patient adverse events were examined. The most reported device problems were due to activation, position, or separation (53.5%). Common indications included defect closures after endoscopic submucosal dissection (ESD) (29.9%) and endoscopic mucosal resection (EMR) (23.9%). From the total reports analyzed, patient adverse events were noted in 21.1% (n  =  30) of cases which comprised of hemorrhage (43.3%; n  =  13), perforation (10.0%; n  =  3), abdominal pain (6.7%; n  =  2) among others.

conclusionsOur analysis of the MAUDE database suggests that the MANTIS

Indexed as

Endoscopic Mucosal ResectionPostoperative ComplicationsSurgical InstrumentsWound Closure TechniquesDatabases, FactualEquipment FailureHumansProduct Surveillance, PostmarketingUnited StatesAnchor prong clipsDefect closureEndoscopic mucosal resection (EMR)Endoscopic submucosal dissection (ESD)MANTIS clipsPeroral endoscopic myotomy (POEM)

Identifiers

PMID41667695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.