Evidence map›Paper›PMID 41667638›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

Neuropsychiatric illness in the later years of life: summary and synthesis.

Charles F Reynolds Iii, Olusola Ajilore

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Charles F Reynolds IiiDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. cfreynoldsiii@gmail.com.
Olusola AjiloreDepartment of Psychiatry, University of Illinois-Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-0737-0437

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dealing with neuropsychiatric illness in the later years of life is an immersion in complexity, born of heterogeneity in etiology, pathogenesis, clinical presentation, and response to intervention. We offer here a conceptual summary and synthesis of the key theme of heterogeneity, as embodied in the 20 papers that constitute this issue of Neuropsychopharmacology Reviews (NPPR's). We conclude with future scientific directions and moral imperatives for research and practice, already underway in many instances, but gaining in speed and transformative potential (especially in generative Artificial Intelligence and Large Language Models). We seek to review and to encourage research that works toward practical wisdom-- what Aristotle termed "phronesis," for promotion of resilience and wellbeing in older adults both at the individual and population levels.

Identifiers

PMID41667638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.