ArticleTranslational psychiatry2026
Early-life sleep disruption in Shank3-deficient rats: A preclinical model for autism-related sleep mechanisms and interventions.
Article in Translational psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Excitation/Inhibition Balance as a Mechanistic Link Between Sleep Disturbance and Autism Spectrum Disorder: A Bidirectional Framework.Alpha psychiatry · 2026Review
- Understanding the Complexity of Sleep Disturbances in ASD: From Mechanisms to Management.Diagnostics (Basel, Switzerland) · 2026Review
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Authors and funding
10 authors.
Funding
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Abstract
Sleep disturbances are among the most prevalent and early-emerging features of autism spectrum disorder (ASD), often preceding core behavioral symptoms. Despite their clinical relevance, the neurobiological mechanisms driving early-life sleep disruption in ASD remain poorly understood. Shank3, encoding a synaptic scaffolding protein at excitatory synapses, is one of the most well-established monogenic risk factors for ASD. Here, we systematically investigated sleep architecture and homeostatic regulation in juvenile Shank3
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