ReviewAnesthesia and pain medicine2026
Frailty assessment in perioperative geriatric patients: a narrative review.
Review in Anesthesia and pain medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between frailty and postoperative delirium after transcatheter aortic valve replacement: a meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Selection of an Appropriate Tool for Assessing Geriatric Frailty in Clinical Practice: A Narrative Review.Clinical interventions in aging · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is increasingly recognized as a major determinant of perioperative risk in the geriatric population. It is characterized by reduced physiological reserve and impaired stress tolerance and arises from multisystem dysregulation involving chronic inflammation, neuroendocrine changes, sarcopenia, and organ dysfunction. Unlike chronological aging, frailty reflects biological vulnerability independent of comorbidity or disability and is strongly associated with postoperative complications, prolonged hospitalization, cognitive decline, and mortality. Therefore, early and systematic frailty assessment is essential to optimize perioperative management, support clinical decision-making, and implement tailored interventions. Multiple validated frailty assessment strategies exist, ranging from phenotypic models such as the Fried Frailty Phenotype to deficit accumulation tools such as the Frailty Index (FI). Practical bedside instruments, including the Clinical Frailty Scale, Edmonton Frail Scale, fatigue, resistance, ambulation, illnesses, loss of weight (FRAIL) questionnaire, modified FI, and disease-specific screening tools, enable rapid detection in clinical settings. Frailty assessment should be performed early and efficiently to facilitate targeted prehabilitation, nutritional optimization, and cognitive support, all of which have been associated with improved functional outcomes. It also informs individualized anesthetic strategies, including drug titration, hemodynamic stabilization, lung-protective ventilation, and delirium prevention. However, barriers to implementation-such as limited clinician awareness, time constraints, and lack of standardized protocols-continue to hinder routine use. Future integration may be accelerated by artificial intelligence, telemedicine, and digital monitoring technologies to enhance geriatric anesthesia. This review provides a comprehensive overview of frailty in geriatric patients, highlighting its definition, pathophysiology, assessment methods, and clinical impact.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.