Evidence map›Paper›PMID 41667139›Full record

ArticleJournal of periodontal & implant science2026

Bone regenerative capacity of the newly synthesized material QG3030: an

Nguyen Pham-Hanh Luong, Kyoung-Hwa Kim, Ji-Eun Kook, Yang-Jo Seol

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of periodontal & implant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nguyen Pham-Hanh Luong *Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-9669-4147
Kyoung-Hwa Kim *Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-5611-1242
Ji-Eun KookDepartment of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0009-0003-6141-8937
Yang-Jo SeolDepartment of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea. yjseol@snu.ac.kr.ORCID https://orcid.org/0000-0002-2076-5452

Funding

Ministry of SMEs and Startups S3326863National Research Foundation of Korea 2021R1A6A1A03039462
6 · The paper itself

Abstract

purposeCurrent bone grafting materials often lack inherent osteoinductive properties, underscoring the need for new therapeutic agents that promote regeneration. In this study, we evaluated the effects of QG3030, a novel osteoinductive derivative of lappaconitine, on the proliferation and osteogenic differentiation of rat bone marrow-derived stem cells (BMSCs)

methodsThe effects of QG3030 on BMSC proliferation and osteogenic differentiation were assessed

results

conclusionsCombining QG3030 with DBBM significantly enhanced bone regeneration in a rat calvarial critical-sized defect model, with QG3030 demonstrating distinct osteogenic effects both

Indexed as

AlkaloidsAnimal modelsBone regenerationBone substitutesMesenchymal stem cellsOsteogenesis

Identifiers

PMID41667139
PMCPMC13150359

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.