Evidence map›Paper›PMID 41666017›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2025

Impact of indoor ventilation on TB transmission risk: implications of climate change.

B Sack, P Shah, K M Abdul Basith, M R Dauphinais, K Jain, M F Martins, S Wallace, S Lakshminarayanan, C Cintron, S Subramanian and 7 more

Abstract read
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In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Air conditioning, ventilation, and respiratory virus transmission potential in South India.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

B SackUniversity of Virginia School of Medicine, Charlottesville, VA, USA.
P ShahSection of Infectious Diseases, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
K M Abdul BasithJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
M R DauphinaisBoston Medical Center, Boston, MA, USA.
K JainJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
M F MartinsSection of Infectious Diseases, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA;, Boston Medical Center, Boston, MA, USA.
S WallaceSection of Infectious Diseases, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA;, Boston Medical Center, Boston, MA, USA.
S LakshminarayananJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
C CintronBoston Medical Center, Boston, MA, USA.
S SubramanianJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
A SahayJohns Hopkins University, Baltimore, MD, USA.
K G KouraInternational Union Against Tuberculosis and Lung Disease, Paris, France;, UMR261 MERIT, Université Paris Cité, IRD, Paris, France.
L PischelYale Department of Internal Medicine, Section of Infectious Diseases, New Haven, CT, USA;, Yale Institute of Global Health, New Haven, CT, USA.
R BrooksYale University School of Medicine, AIDS Program, New Haven, CT, USA.
S ShenoiYale University School of Medicine, AIDS Program, New Haven, CT, USA.
P ChinnakaliJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
P SinhaSection of Infectious Diseases, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA;, Boston Medical Center, Boston, MA, USA.

Funding

Investigation of within Household Transmission of Influenza in Low-Resource SettingsK23AI180337 · NIAID · YALE UNIVERSITY · PI Lauren Elizabeth Pischel · 2024 to 2026
$559k
Nutritional Interventions to End Tuberculosis among Persons with HIV (NUTRIENT)K01AI167733 · NIAID · BOSTON MEDICAL CENTER · PI Pranay Sinha · 2023 to 2026
$512k
NIAID NIH HHS K01 AI167733NIAID NIH HHS K23 AI180337
6 · The paper itself

Abstract

<sec><title>BACKGROUND</title>Due to rising temperatures, individuals are predicted to spend more time in under-ventilated indoor spaces, increasing TB transmission risk. We studied the impact of indoor ventilation on TB transmission risk in homes of persons with TB and in health care facilities in Puducherry, India.</sec><sec><title>METHODS</title>We measured ventilation in air changes per hour (ACH) under different ventilation conditions using a carbon dioxide decay method. We estimated transmission risk using the Wells-Riley equation.</sec><sec><title>RESULTS</title>Forty-five measurements were taken in 13 homes and 7 health care spaces. In the closed condition (doors and windows closed, fans off), ACH was low (mean 2.23, standard deviation [SD] 2.27) and TB transmission risk was high at 62% (SD 31%). When air conditioning (AC) was on, ACH reduced to 0.75 (SD 0.51), and TB transmission was highest at 76% (SD 13%). Natural ventilation significantly improved ACH (mean 9.46, SD 3.90;

Indexed as

Air ConditioningAir MicrobiologyAir Pollution, IndoorTuberculosis, PulmonaryVentilationAir FiltersCross-Sectional StudiesGlobal WarmingHealth FacilitiesHome EnvironmentHumansIndiaObservational Studies as TopicPilot ProjectsRisk AssessmentRisk Factors

Identifiers

PMID41666017
PMCPMC13353448

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.