Evidence map›Paper›PMID 41665985›Full record

ArticleBioinformatics (Oxford, England)2026

UCell and pyUCell: single-cell gene signature scoring for R and Python.

Massimo Andreatta, Santiago J Carmona

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. AbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Massimo AndreattaDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva 1206, Switzerland.ORCID 0000-0002-8036-2647
Santiago J CarmonaDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva 1206, Switzerland.ORCID 0000-0002-2495-0671

Funding

Swiss Cancer Research Foundation KFS-5409-08-2021
6 · The paper itself

Abstract

summaryGene signature scoring provides a simple yet powerful approach for quantifying biological signals within single-cell omics datasets. UCell and pyUCell offer fast and robust implementations of rank-based signature scoring for R and Python, respectively, integrating seamlessly with leading single-cell analysis ecosystems such as Seurat, Bioconductor, and scanpy/scverse. AVAILABILITY AND IMPLEMENTATION: UCell v2 is distributed as an R package by BioConductor (https://bioconductor.org/packages/UCell/) and as a Python package by pyPI (https://pypi.org/project/pyucell/).

Indexed as

Computational BiologyGene Expression ProfilingSingle-Cell AnalysisSoftwareSingle-Cell Gene Expression Analysis

Identifiers

PMID41665985
PMCPMC12925249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.