Trial reportEuropean child & adolescent psychiatry2026
Effects of virtual reality eye movement desensitization and reprocessing therapy for adolescents with major depressive disorder: a functional Near-Infrared spectroscopy study.
Trial report in European child & adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Virtual reality in psychological interventions for mood disorders: a scoping review.BMC psychiatry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Virtual Reality-based Eye movement desensitization and reprocessing therapy (VR-EMDR) has been proven effective in treating adults with major depressive disorder (MDD). However, its effectiveness in treating adolescents with MDD is less studied, and its underlying neuroimaging mechanism remains unknown. Sixty-eight adolescents with MDD and 29 adolescent healthy control (HC) were recruited. Adolescents with MDD were randomly allocated to the intervention group and the wait-list control group. The intervention group received 12-session of VR-EMDR, while another group received no psychotherapy. We used the Hamilton Depression Rating Scale-24 version (24-HDRS) to assess the patients’ depressive symptoms; the Das-Naglieri Cognitive Assessment System (CAS) to assess the patients’ neurocognitive performance; and the functional near-infrared spectroscopy (fNIRS) to assess the patients’ functional connectivity and small-world network attributes. After VR-EMDR, the linear mixed model (LMM) revealed significantly lower scores in 24-HDRS and average shortest path, and significantly higher scores in figure memory, successive processing, sentence repetition, sentence question, and total cognitive in the intervention group (all p < 0.05). Multiple linear regression analyses revealed that significant negative relationships can be found between average shortest path and figure memory, total cognition; a significant positive relationship can be found between global efficiency and successive processing (all p < 0.05). VR-EMDR can effectively improve depressive symptoms, neurocognitive performance, and change small-world network attributes in adolescents with MDD. Furthermore, the changes in average shortest path length and global efficiency may play potential roles in the improvement of cognitive function after VR-EMDR.
Indexed as
Identifiers
41665686What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.