Evidence map›Paper›PMID 41665607›Full record

ArticleMedical physics2026

Combining flat-panel imaging with internal BB markers for precise HDR brachytherapy source localization: A simulation study.

Yibin Ling, Catherine H Frank, Naoki Dominguez Kondo, Jose Ramos Mendez, Ke Sheng, Qihui Lyu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yibin LingDepartment of Nuclear Engineering, University of California, Berkeley, CA, USA.
Catherine H FrankDepartment of Radiation Oncology, University of California, San Francisco, CA, USA.
Naoki Dominguez KondoDepartment of Radiation Oncology, University of California, San Francisco, CA, USA.
Jose Ramos MendezDepartment of Radiation Oncology, University of California, San Francisco, CA, USA.
Ke ShengDepartment of Radiation Oncology, University of California, San Francisco, CA, USA.
Qihui LyuDepartment of Radiation Oncology, University of California, San Francisco, CA, USA.

Funding

Development of a versatile robotic radiation therapy systemR44CA183390 · NCI · RADIABEAM TECHNOLOGIES, LLC · PI SHENG, KE, YONEMOTO, JAY · 2017 to 2024
$5.8M
Precision breast radiotherapy with the soft robot and supine CTR01EB031577 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JIN, LIHUA, SHENG, KE · 2022 to 2025
$1.5M
NCI NIH HHS R44 CA183390NIBIB NIH HHS R01 EB031577NIH HHS R01EB031577NIH HHS R44CA183390
6 · The paper itself

Abstract

backgroundHigh Dose Rate (HDR) brachytherapy delivers concentrated radiation to the tumor by placing a high-dose-rate radioactive source directly inside the target. However, the sharp dose falloff also increases susceptibility to errors and uncertainties. PURPOSE: To enhance source localization accuracy relative to room coordinates and the implant, we optimize the design of a flat-panel-based source localization system for HDR brachytherapy.

methodsGamma rays from the Ir-192 Flexisource were simulated with Monte Carlo for image reconstruction. A 50 × 50 cm

resultsRelative to the room coordinates using the couch-BBs, the proposed system achieves 0.78 mm accuracy. Localization error increases with larger BSD and smaller BDD, ranging from 0.3-2.5 mm (BSD: 10-30 cm) and 0.3-1.2 mm (BDD: 30-10 cm). Introducing implant motion (15 mm translation, 10

conclusionThe study demonstrates the feasibility of using a flat-panel detector, couch-attached markers, and a dummy wire for robust localization of the HDR brachytherapy source relative to both the room coordinates and the implant.

Indexed as

BrachytherapyFiducial MarkersMonte Carlo MethodTungstenImage Processing, Computer-AssistedRadiotherapy DosageTungstenbrachytherapyHDR techniquesimage‐guided therapy

Identifiers

PMID41665607
PMCPMC12889218

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