Evidence map›Paper›PMID 41665187›Full record

ArticleACS infectious diseases2026

Rapid Adaptive Evolution under Combination Therapy in

Camila Maurmann de Souza, Amy Lee, Osmel Fleitas Martínez, Kevin Ning, Mylena Cardoso da Costa, Mariana Rocha Maximiano, Gabriel Cidade Feitosa, Yasmim Neiva, Marcelo Campos, Marcelo Ramada and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Camila Maurmann de SouzaCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Amy LeeDepartment of Molecular Biology and Biochemistry, Simon Fraser University, South Sciences Building 7107, 8888 University Drive, Burnaby V5A 1S6, British Columbia, Canada.
Osmel Fleitas MartínezCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.ORCID 0000-0001-7505-6146
Kevin NingDepartment of Molecular Biology and Biochemistry, Simon Fraser University, South Sciences Building 7107, 8888 University Drive, Burnaby V5A 1S6, British Columbia, Canada.
Mylena Cardoso da CostaCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Mariana Rocha MaximianoCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Gabriel Cidade FeitosaCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Yasmim NeivaCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Marcelo CamposIntegrative Plant Research Laboratory, Programa de Pós-Graduação Em Biologia Vegetal, Universidade Federal de Mato Grosso, Cuiaba 78060-900, Brazil.
Marcelo RamadaCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Sérgio AlencarCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.
Robert E W HancockCentre for Microbial Diseases and Immunity Research, University of British Columbia, 2259 Lower Mall Research Station, Vancouver V6T 1Z4, British Columbia, Canada.ORCID 0000-0001-5989-8503
Octávio Luiz FrancoCentro de Análises Proteômicas e Bioquímicas, Programa de Pós-Graduação Em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília 71966-700, Brazil.ORCID 0000-0001-9546-0525

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeAdaptation, PhysiologicalBacterial ProteinsDrug Therapy, CombinationEvolution, MolecularGene Expression Regulation, BacterialGenome, BacterialHumansTime FactorsTranscription, GeneticAnti-Bacterial AgentsBacterial Proteinsantibiotic resistancebacteriaevolutiongenomicsinfectious diseaseK. pneumoniae

Identifiers

PMID41665187
PMCPMC13162261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.