Evidence map›Paper›PMID 41664741›Full record

ArticleCureus2026

Balancing Early Detection and Biopsy Risks in Sub-centimeter Lung Nodules: A Case Series.

Joseph O Odeyemi, Leah Whitis, Reem Mumtaz, Abdel-Ghanie Abu-Samra

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph O OdeyemiInternal Medicine/Pediatrics, University of Kansas School of Medicine, Wichita, USA.
Leah WhitisInternal Medicine/Pediatrics, University of Kansas School of Medicine, Wichita, USA.
Reem MumtazInternal Medicine, University of Kansas School of Medicine Wichita, Wichita, USA.
Abdel-Ghanie Abu-SamraPulmonology/Critical Care, University of Kansas School of Medicine Wichita, Wichita, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary nodules smaller than 8 mm are often monitored over time. In some patients, these nodules may grow while under observation, occasionally representing aggressive disease. We describe three patients with initially small pulmonary nodules that demonstrated significant growth during follow-up. Two were ultimately found to have small-cell lung carcinoma, and one had probable non-small cell carcinoma. These cases highlight the potential limitations of delayed tissue sampling and suggest that earlier diagnostic evaluation may be beneficial in certain patients. Advanced bronchoscopic techniques can allow safe and accurate biopsy of small, peripheral nodules. Earlier intervention in patients with growing nodules could support timely treatment and improve outcomes.

Indexed as

ct-guided biopsyearly cancer detectionlung cancer screeningpulmonary nodulesrobotic bronchoscopy

Identifiers

PMID41664741
PMCPMC12883267

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.