Evidence map›Paper›PMID 41664739›Full record

ArticleCureus2026

Examining Tympanostomy Tube Risk by Breastfeeding Duration: Is Six Months Enough?

Raj Patel, Germaine Harvery, Rebecca Maddrell

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raj PatelOtolaryngology-Head and Neck Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, USA.
Germaine HarveryOtolaryngology-Head and Neck Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, USA.
Rebecca MaddrellFamily Medicine, Loyola University Medical Center, Maywood, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreastfeeding provides passive immunoglobulin A (IgA) immunity to newborns, supporting proper sinonasal, pulmonary, and mucosal protection. Current recommendations advise breastfeeding for at least six months before introducing complementary foods, with continuation encouraged for up to two years. Infants who are not breastfed are at increased risk for sinopulmonary infections, including acute otitis media. Recurrent or chronic acute otitis media can lead to tympanostomy tube placement. While this highlights the protective role of breastfeeding, there is limited data on whether extending breastfeeding beyond six months offers additional protection against the need for tympanostomy tube insertion.

objectiveThis study aimed to evaluate whether longer durations of breastfeeding provide additional protection against tympanostomy tube placement in pediatric patients.

methodsA retrospective chart review was conducted to evaluate pediatric patients who underwent tympanostomy tube placement using Current Procedural Terminology (CPT) codes 69436 and 69433 and a control group matched by age and gender. Feeding type was classified as formula-fed or breastfed, with breastfeeding duration recorded to the best of available documentation. Children who received both breast milk and formula were considered breastfed. Chi-squared tests and risk ratios were used to analyze the association between breastfeeding duration and tympanostomy tube placement.

resultsAmong 500 pediatric patients, breastfeeding duration was significantly associated with tympanostomy tube insertion (χ²=9.36; p=0.025). Children breastfed for less than six months or not at all had a tube insertion rate of 20.8% (reference). Those breastfed for six months had a rate of 11.6% (RR: 0.72; p=0.025). Children breastfed for more than six months had a rate of 8.4% (RR: 0.79; p=0.08). Those breastfed for more than 12 months had a rate of 9% (RR: 0.95; p=0.08). Pairwise comparisons between children breastfed for six months and those breastfed for more than six months (χ²=0.24; p=0.63) or more than 12 months (χ²=2.99; p=0.084) were not statistically significant.

conclusionBreastfeeding for up to six months is associated with a lower risk of tympanostomy tube insertion compared to children breastfed for shorter than six months or not breastfed at all. Continuing breastfeeding beyond six months and 12 months does not appear to provide additional protective benefit.

Indexed as

breastfeeding durationearly-life immune protectionpassive immunityrecurrent acute otitis mediatympanostomy tube

Identifiers

PMID41664739
PMCPMC12883229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.