Evidence map›Paper›PMID 41664728›Full record

ArticleCureus2026

A Case of Familial Paroxysmal Non-kinesigenic Dyskinesia in Mainland China: A Clinical and Genetic Investigation.

Wenhan Zhang, Jingwen Li, Ruichuan Xie, Zhongjiao Lu, Nan Zhao, Kan Wang, Yansheng Li, Shuang Li, Gang Wang, Li Gao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Novel advanced patient-derivedFrontiers in neurology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenhan ZhangDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Jingwen LiDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Ruichuan XieDepartment of Neurology, Sanya People's Hospital, Sanya, CHN.
Zhongjiao LuDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Nan ZhaoDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Kan WangDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Yansheng LiDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Shuang LiDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Gang WangDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.
Li GaoDepartment of Neurology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, CHN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paroxysmal non-kinesigenic dyskinesia (PNKD) is an autosomal dominant condition characterized by recurring dystonia or mixed chorea and ballism caused by emotional stress, exhaustion, coffee, alcohol, menstruation, and other factors. Here, we provide a large family PNKD pedigree from mainland China, where the same c.20C4T (p.Ala7Val) mutation in exon 1 of the PNKD gene was genetically confirmed to be present in nine affected individuals. Here, we report a rarely described Asian PNKD pedigree and aim to widen the clinical and genetic spectrum of PNKD while also providing fresh diagnostic insights for this rare condition.

Indexed as

case reportmutationmyofibrillogenesis regulatorparoxysmal dyskinesiasparoxysmal non-kinesigenic dyskinesia

Identifiers

PMID41664728
PMCPMC12883233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.