Evidence map›Paper›PMID 41664360›Full record

ArticleJournal of integrative plant biology2026

Optimizations of Cas12a- and Cas12i-based adenine base editors for efficient precision editing in the plant genome.

Xiaoshuang Liu, Shan Jin, Zhi Xiao, Chong Ma, Qing Wang, Huanhuan Wang, Ruohan Zhou, Dongfang Gu, Rongfang Xu, Ruiying Qin and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Base editing in rice using nuclease-deactivated CRISPR/Cas-SF01.Journal of integrative plant biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoshuang LiuCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0003-5626-2763
Shan JinCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0007-8502-6101
Zhi XiaoCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0004-7431-5387
Chong MaCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0003-4002-6061
Qing WangCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0008-2450-0217
Huanhuan WangCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0001-4183-1017
Ruohan ZhouCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0008-3855-8751
Dongfang GuBio-breeding Laboratory of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230036, China.ORCID https://orcid.org/0009-0002-5557-0724
Rongfang XuBio-breeding Laboratory of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230036, China.ORCID https://orcid.org/0000-0001-8752-8606
Ruiying QinBio-breeding Laboratory of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230036, China.ORCID https://orcid.org/0009-0009-3338-8295
Juan LiBio-breeding Laboratory of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230036, China.ORCID https://orcid.org/0000-0002-4603-1078
Pengcheng WeiCollege of Agronomy, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0009-0006-2955-4324

Funding

This work was supported by the Agriculture Science and Technology Major Project, the Science and Technology Major Project of Anhui Province (No. 202423110050063, No. 202423m10050002, and No. 2023n06020020), the Natural Science Foundation of China (No. 32300343, No.32572441, and No. 32570484), and Yangtze River Delta Science and Technology Innovation Community Joint Research (Basic Research) Project (No. 2024CSJZN01100).
6 · The paper itself

Abstract

A strategy coupling high-activity nucleases with dimeric TadA-8e optimizes plant Cas12-based adenine base editors, boosts editing efficiency, and provides precise editors for crop breeding and genomics research.

Indexed as

AdenineCRISPR-Cas SystemsGene EditingGenome, PlantAdenine

Identifiers

PMID41664360
PMCPMC13545824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.