Evidence map›Paper›PMID 41664289›Full record

SynthesisJournal of occupational and environmental medicine2026

Understanding the Neurologic and Cognitive and Behavioral Effects Associated With Exposures to Jet Fuels: A Fit-for-Purpose Systematic Literature Review.

Jenna L N Sprowles, Barrett D Allen, Alex J Lindahl, Lisa M Prince, Emma C Bowers, Elizabeth M Martin, Anna Kolanowski, Mary Lundin, Samantha J Goodman, Hannah M Starnes and 6 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of occupational and environmental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jenna L N SprowlesFrom the ICF, Reston, Virginia (J.L.N.S., B.D.A., A.J.L., L.M.P., E.C.B., E.M.M., A.K., M.L., S.J.G., H.M.S., S.E.A.G., S.J.S., S.E.E., C.E.H.); Airborne Hazards and Burn Pits Center of Excellence, War Related Illness and Injury Study Center, US Department of Veterans Affairs, East Orange, New Jersey (M.R.); and Exposure Science Program, Health Outcomes Military Exposures, Veterans Health Administration, US Department of Veterans Affairs, Washington, DC (T.D.V.H.).ORCID 0000-0001-6198-8057
Elizabeth M MartinORCID 0000-0001-8428-7034
Samantha J GoodmanORCID 0000-0003-4828-0964
Sagi Enicole A GilleraORCID 0000-0002-8064-1697
Michelle Robertson
Terra D Vincent-HallORCID 0009-0000-4218-4010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to assess the neurologic, cognitive, and behavioral effects of jet fuels used by the US military.

methodsA fit-for-purpose systematic literature review approach based on the US EPA's IRIS handbook was used to conduct a comprehensive assessment of the scientific evidence. Data were synthesized to evaluate evidence for specific neurologic health outcomes.

resultsShort- and long-term adverse effects on sensory functions (ie, auditory, visual), memory and cognition, motor coordination, and peripheral nervous system were observed in human and animal studies following exposure to jet fuels.

conclusionsThe evidence indicates that exposure to jet fuels is likely to cause neurotoxicity in humans. Overall, the results indicate that the nervous system is sensitive to jet fuel exposure; however, uncertainty remains due to the limited number of quality epidemiologic studies and the large variety of jet fuels studied.

Indexed as

CognitionHydrocarbonsNeurotoxicity SyndromesOccupational ExposureAnimalsHumansMemoryMilitary PersonnelHydrocarbonsJP8 aviation fuelcognitionjet fuelsmemorymotor coordinationneurotoxicityototoxicitysystematic review

Identifiers

PMID41664289
PMCPMC12928831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.