Evidence map›Paper›PMID 41664257›Full record

SynthesisJournal of occupational and environmental medicine2026

Assessing the Carcinogenic Potential of Jet Fuels: A Fit-for-Purpose Systematic Literature Review.

Elizabeth R Heitz, Barrett D Allen, Samantha J Goodman, Anastasia N Freedman, Sarah L Miller, Samantha J Snow, Sorina E Eftim, Cary E Haver, Kate R Weinberger, Justin G Bergeron and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of occupational and environmental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elizabeth R HeitzFrom the Exposure Science Program, Health Outcomes Military Exposures, Department of Veterans Affairs (E.R.H., J.G.B., T.D.V.H.), Washington, DC; and ICF, Reston, Virginia (B.D.A., S.J.G., A.N.F., S.L.M., S.J.S., S.E.E., C.E.H., K.R.W.).ORCID 0009-0007-6996-5475
Samantha J GoodmanORCID 0000-0003-4828-0964
Anastasia N FreedmanORCID 0000-0001-6107-4642
Kate R WeinbergerORCID 0000-0001-6001-0081
Justin G BergeronORCID 0009-0009-2665-8277
Terra D Vincent-HallORCID 0009-0000-4218-4010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to determine whether exposures to jet fuels lead to cancer-related health effects.

methodsA systematic literature review was conducted following the US EPA's IRIS handbook, incorporating epidemiologic, animal toxicological, and mechanistic studies. The carcinogenic potential of jet fuel was assessed according to EPA's 2005 Guidelines for Carcinogen Risk Assessment.

resultsIncreased risks of various cancers, including kidney, bladder, and skin cancers, were observed in humans and animals exposed to jet fuels, which were supported by mechanistic data.

conclusionsThe available studies provide suggestive evidence of carcinogenic potential for jet fuels. However, uncertainty remains because of to the limited number of high-quality epidemiologic studies and the wide variety of jet fuel types examined. Further research is needed to establish a more definitive link between jet fuel exposure and cancer risk.

Indexed as

CarcinogensHydrocarbonsNeoplasmsOccupational ExposureAnimalsHumansRisk AssessmentCarcinogensHydrocarbonscancerjet fuelmilitary exposureneoplasmsoccupational exposuresystematic review

Identifiers

PMID41664257
PMCPMC12928791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.