ArticleTropical medicine and health2026
Management of plica polonica in the wake of refractory head lice infestation: a case report.
Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
backgroundPediculosis capitis remains widespread globally, and the emergence of resistance genes continues to impede eradication efforts. This case of plica polonica offers insight into the complexity and challenges of pediculosis in endemic settings where resistant lice are present. CASE PRESENTATION: We report the case of a 13-year-old girl from a suburban area of Bangkok with long-standing pediculosis that progressed to plica polonica due to prolonged lack of intervention. Molecular analysis of the sampled lice demonstrated a 100% homozygous knockdown resistance (kdr) mutation. Several of her classmates also described recurrent infestations despite previous permethrin use, and permethrin exposure in this case showed limited effect, as lice remained viable after the recommended treatment period. The condition resolved after incorporating physical modalities.
conclusionPediculosis in endemic areas is at a high suspicion for resistance. Chemical treatment alone may not lead to a cure, and caretakers should emphasize other treatment forms to achieve a cure. Such an approach may help prevent further mutations due to inbreeding within the headlice population with resistance genes from the unoptimized chemical treatment.
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